2928-14-5

Basic information

• Product Name: Methyl 3-(4-fluorophenyl)propanoate
• Synonyms: Methyl 3-(4-fluorophenyl)propanoate;Benzenepropanoic acid, 4-fluoro-, Methyl ester
• CAS NO: 2928-14-5
• Molecular Formula: C₁₀H₁₁FO₂
• Molecular Weight: 182.1915432
• Mol File: 2928-14-5.mol
• Article Data: 25

Chemical Properties

• Appearance: /
• Storage Temp.: Room temperature.
• CAS DataBase Reference: Methyl 3-(4-fluorophenyl)propanoate(CAS DataBase Reference)
• NIST Chemistry Reference: Methyl 3-(4-fluorophenyl)propanoate(2928-14-5)
• EPA Substance Registry System: Methyl 3-(4-fluorophenyl)propanoate(2928-14-5)

Safety Data

• Hazardous Substances Data: 2928-14-5(Hazardous Substances Data)

Usage

General Description

Methyl 3-(4-fluorophenyl)propanoate, also known as methyl 4-fluorophenyl-3-acrylate, is an organic compound with the chemical formula C11H11FO2. It is a methyl ester derivative of 4-fluorophenylpropanoic acid, with a molecular weight of 192.2 g/mol. This chemical compound is commonly used as an intermediate in the synthesis of pharmaceuticals, agrochemicals, and other organic compounds. It is a white to light yellow solid with a faint odor, and it is soluble in organic solvents such as ethanol and methanol. Methyl 3-(4-fluorophenyl)propanoate is flammable and should be handled and stored with appropriate safety measures in place.

Upstream product

• 459-31-4 3-(4-fluorophenyl)propanoic acid 
• 18107-18-1 diazomethyl-trimethyl-silane 
• 96426-60-7 methyl (2E)-3-(4-fluorophenyl)-2-propenoate 
• 67-56-1 methanol 
• 201230-82-2 carbon monoxide 
• 403-41-8 1-(4-Fluorophenyl)ethanol 
• 459-57-4 4-fluorobenzaldehyde 
• 100891-10-9 methyl p-fluorocinnamate 
• 405-99-2 para-fluorostyrene 
• 124-38-9 carbon dioxide 
• 459-32-5 (E)-4-fluorocinnamic acid 
• 186581-53-3 diazomethane 

Downstream Products

• 1481-32-9 6-fluoroindan-1-one 
• 63416-70-6 3-(4-fluorophenyl)propanal 
• 5107-21-1 3-(4-fluorophenyl)propanehydrazide 
• 702-15-8 3-(4-fluorophenyl)propan-1-ol 
• 1374135-23-5 methyl 3-[4-fluoro-3-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)phenyl]propanoate 
• 1261880-43-6 methyl 3-(4-fluoro-3-iodophenyl)propanoate 
• 623577-33-3 5-(4-fluorophenyl)-1-methyl-1, 2-dihydropyrazol-3-one 
• 777953-39-6 5-(4-fluorophenyl)-2-methyl-1,2-dihydropyrazol-3-one 

Relevant articles and documents

Ligand-controlled cobalt-catalyzed remote hydroboration and alkene isomerization of allylic siloxanes

The Co-catalyzed remote hydroboration and alkene isomerization of allylic siloxanes were realized by a ligand-controlled strategy. The remote hydroboration with dcype provided borylethers, while xantphos favored the formation of silyl enol ethers.

Nickel-Catalyzed Alkyl-Alkyl Cross-Electrophile Coupling Reaction of 1,3-Dimesylates for the Synthesis of Alkylcyclopropanes

Cross-electrophile coupling reactions of two Csp3-X bonds remain challenging. Herein we report an intramolecular nickel-catalyzed cross-electrophile coupling reaction of 1,3-diol derivatives. Notably, this transformation is utilized to synthesize a range of mono- and 1,2-disubstituted alkylcyclopropanes, including those derived from terpenes, steroids, and aldol products. Additionally, enantioenriched cyclopropanes are synthesized from the products of proline-catalyzed and Evans aldol reactions. A procedure for direct transformation of 1,3-diols to cyclopropanes is also described. Calculations and experimental data are consistent with a nickel-catalyzed mechanism that begins with stereoablative oxidative addition at the secondary center.

Iron-catalysed 1,2-aryl migration of tertiary azides

1,2-Aryl migration of α,α-diaryl tertiary azides was achieved by using the catalytic system of FeCl2/N-heterocyclic carbene (NHC) SIPr·HCl. The reaction generated aniline products in good yields after one-pot reduction of the migration-resultant imines.