29363-98-2

Basic information

• Product Name: 3-(4-chloro-phenyl)-isoxazole-4-carboxylic acid ethyl ester
• Synonyms: 3-(4-chloro-phenyl)-isoxazole-4-carboxylic acid ethyl ester
• CAS NO: 29363-98-2
• Molecular Weight: 251.669
• Mol File: 29363-98-2.mol
• Article Data: 8

Chemical Properties

• CAS DataBase Reference: 3-(4-chloro-phenyl)-isoxazole-4-carboxylic acid ethyl ester(CAS DataBase Reference)
• NIST Chemistry Reference: 3-(4-chloro-phenyl)-isoxazole-4-carboxylic acid ethyl ester(29363-98-2)
• EPA Substance Registry System: 3-(4-chloro-phenyl)-isoxazole-4-carboxylic acid ethyl ester(29363-98-2)

Safety Data

• Hazardous Substances Data: 29363-98-2(Hazardous Substances Data)

Upstream product

• 81239-00-1 ethyl (E)-3-(piperidin-1-yl)acrylate 
• 28123-63-9 4-chlorobenzohydroximoyl chloride 
• 104-88-1 4-chlorobenzaldehyde 
• 104-83-6 1-Chloro-4-(chloromethyl)benzene 
• 623-47-2 propynoic acid ethyl ester 
• 65651-80-1 ethyl (E)-3-(pyrrolidin-1-yl)acrylate 
• 922-67-8 propynoic acid methyl ester 
• 924-99-2 ethyl 3-(dimethylamino)acrylate 
• 121-44-8 triethylamine 
• 3848-36-0 4-chlorobenzaldoxime 

Downstream Products

• 1048922-51-5 3-(4-chloro-phenyl)-isoxazole-4-carboxylic acid 
• 1159603-80-1 6-[3-(4-chloro-phenyl)-isoxazol-4-ylmethoxy]-nicotinic acid methyl ester 
• 1159603-82-3 6-[3-(4-chloro-phenyl)-isoxazol-4-ylmethoxy]-N-isopropyl-nicotinamide 
• 1159603-85-6 6-[3-(4-chloro-phenyl)-isoxazol-4-ylmethoxy]-nicotinic acid 
• 1159603-87-8 6-[3-(4-chloro-phenyl)-isoxazol-4-ylmethoxy]-N-(3-hydroxy-propyl)-nicotinamide 

Relevant articles and documents

Design, synthesis and SAR of a novel series of heterocyclic phenylpropanoic acids as GPR120 agonists

A novel series of 5-membered heterocycle-containing phenylpropanoic acid derivatives was discovered as potent GPR120 agonists with low clearance, high oral bioavailability and in vivo antidiabetic activity in rodents.

PROCESS FOR THE PREPARATION OF ISOXAZOLYL-METHOXY-NICOTINIC ACIDS

The present invention relates to a process for the preparation of a compound of formula (I) which is useful as an intermediate in the preparation of active pharmaceutical compounds from a compound of formula (IV) wherein R1 and R2 ar