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294182-06-2

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294182-06-2 Usage

General Description

2-(5-bromopyridin-2-yl)-1-(2,4-difluorophenyl)-2,2-difluoroethanone is a chemical compound with the molecular formula C13H7BrF4N2O. It is a yellow solid with a molecular weight of 362.11 g/mol. 2-(5-bromopyridin-2-yl)-1-(2,4-difluorophenyl)-2,2-difluoroethanone is a ketone derivative that contains bromine, fluorine, and nitrogen atoms in its structure. It may be used as a building block in the synthesis of other organic compounds or as a reagent in chemical reactions. It is important to handle this compound with caution and use appropriate safety measures, as it may be hazardous if not handled properly.

Check Digit Verification of cas no

The CAS Registry Mumber 294182-06-2 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 2,9,4,1,8 and 2 respectively; the second part has 2 digits, 0 and 6 respectively.
Calculate Digit Verification of CAS Registry Number 294182-06:
(8*2)+(7*9)+(6*4)+(5*1)+(4*8)+(3*2)+(2*0)+(1*6)=152
152 % 10 = 2
So 294182-06-2 is a valid CAS Registry Number.

294182-06-2Downstream Products

294182-06-2Relevant articles and documents

Fungal lanosterol 14α-demethylase (CYP51) inhibitor Treatment of recurrent vulvovaginal candidiasis Treatment of onychomycosis

Chopra, S.,Dasgupta, A.,Thakare, R.

, p. 855 - 868 (2020/01/21)

Developing a rationally designed, more selective azole antifungal agent that specifically targets the fungal CYP51 over the host CYP51 is a severe unmet need considering a massive shortfall in novel antifungal agents. In this context, oteseconazole (VT-1161) represents a very exciting new development targeting serious fungal infections caused by a wide variety of fungal pathogens including multidrug-resistant Candida responsible for recurrent vulvovaginal candidiasis. This monograph details the various in vitro and in vivo properties exhibited by oteseconazole as well as its current status in clinical trials.

METALLOENZYME INHIBITOR COMPOUNDS

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Page/Page column 80; 81, (2017/07/31)

The instant invention describes compounds having metalloenzyme modulating activity, and methods of treating diseases, disorders or symptoms thereof mediated by such metalloenzymes.

ANTIFUNGAL COMPOUND PROCESS

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Page/Page column 56, (2015/11/11)

The present invention relates to a process for preparing compound 1 that is useful as an antifungal agent. In particular, the invention seeks to provide new methodology for preparing compound 1 and substituted derivatives thereof.

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