2942-07-6

Basic information

• Product Name: 5-NITROBENZOTHIAZOLE
• Synonyms: 5-NITROBENZOTHIAZOLE;Benzothiazole, 5-nitro- (6CI,7CI,8CI,9CI);5-nitro-1,3-benzothiazole;Benzothiazole,5-nitro-
• CAS NO: 2942-07-6
• Molecular Formula: C₇H₄N₂O₂S
• Molecular Weight: 180.18
• Product Categories: BENZOTHIAZOLE
• Mol File: 2942-07-6.mol
• Article Data: 9

Chemical Properties

• Melting Point: 163-164℃
• Boiling Point: 333.7 °C at 760 mmHg
• Flash Point: 155.6 °C
• Appearance: /
• Density: 1.525 g/cm³
• Vapor Pressure: 0.000261mmHg at 25°C
• Refractive Index: 1.729
• Storage Temp.: 2-8°C
• PKA: -0.87±0.10(Predicted)
• CAS DataBase Reference: 5-NITROBENZOTHIAZOLE(CAS DataBase Reference)
• NIST Chemistry Reference: 5-NITROBENZOTHIAZOLE(2942-07-6)
• EPA Substance Registry System: 5-NITROBENZOTHIAZOLE(2942-07-6)

Safety Data

• HazardClass: IRRITANT
• Hazardous Substances Data: 2942-07-6(Hazardous Substances Data)

Usage

Chemical Properties

Yellow solid

InChI:InChI=1/C7H4N2O2S/c10-9(11)5-1-2-7-6(3-5)8-4-12-7/h1-4H

Upstream product

• 6283-25-6 H₂NC₆H₃(Cl)NO₂ 
• 10403-47-1 2-bromo 5-nitroaniline 
• 64-18-6 formic acid 
• 2258-42-6 formyl acetic anhydride 
• 758-16-7 N,N-dimethylthioformamide 
• 97-00-7 1-chloro-2,4-dinitro-benzene 
• 98556-09-3 N-(2-bromo-5-nitrophenyl)formamide 
• 32403-70-6 2-(2,4-dinitro-phenylsulfanyl)-propionic acid 
• 32403-69-3 2-(2,4-dinitrophenylthio)acetic acid 
• 58759-63-0 5-nitrobenzo[d]thiazole-2(3H)-thione 
• 53666-48-1 N-(2-chloro-5-nitrophenyl)formamide 

Downstream Products

• 36894-62-9 N-phenylbenzo[d]thiazol-5-amine 
• 256415-35-7 C₁₄H₁₁N₃S₂ 
• 1360449-09-7 1,3-di(benzo[d]thiazol-5-yl)thiourea 
• 256415-12-0 C₁₄H₁₁N₃OS 
• 73458-39-6 5-nitro-benzothiazol-2-ylamine 
• 769-19-7 4-bromobenzo[d]thiazol-5-amine 
• 24311-40-8 3-nitroaniline-6-sulphonic acid 
• 1123-93-9 5-aminobenzothiazole 
• 36894-61-8 N-(benzo[d]thiazol-5-yl)acetamide 
• 50480-29-0 benzo[d]thiazole-2,5-diamine 
• 501-60-0 1,2-di(p-tolyl)diazene 
• 501-58-6 (E)-1,2-bis(4-methoxyphenyl)diazene 
• 1602-00-2 bis-(4-chloro-phenyl)-diazene 
• 63788-88-5 4-butyl-5-nitroso-benzothiazole 

Relevant articles and documents

ACTIVATORS OF THE RETINOIC ACID INDUCIBLE GENE "RIG-I' PATHWAY AND METHODS OF USE THEREOF

The present invention is directed to compounds of Formula (I), which are activators of the RIG-I pathway.

Method for synthesizing benzothiazole by microwave radiation of benzothioamide compound in aqueous phase

The invention discloses a method for synthesizing benzothiazole by microwave radiation of a benzothioamide compound in an aqueous phase. The method includes the steps: adding the benzothioamide compound into the aqueous phase under microwave conditions; performing cyclization under alkaline conditions to generate the benzothiazole. The method for preparing the benzothiazole is environmentally friendly, simple and convenient in operation, safe, cheap and efficient. Compared with the prior art, the method is applicable to a lot of functional groups, high in yield, few in by-products, simple in operation, safe, low in cost and environmentally friendly.

Structure-activity relationships of N-phenyl-N′-benzothiazol-6-ylurea synthetic derivatives: Cytokinin-like activity and adventitious rooting enhancement

Some years ago we demonstrated the cytokinin-like activity of the synthetic N-phenyl-N′-benzothiazol-6-ylurea (PBU) and a relevant adventitious rooting adjuvant activity of symmetric urea derivatives devoid of any cytokinin- or auxin-like activity per se. Here we report the synthesis and the biological activity evaluation of nine symmetric or asymmetric ureas/thioureas, structurally related to PBU. None of them show cytokinin-like activity, while we demonstrate for the first time that PBU interacts with Arabidopsis cytokinin receptor CRE1/AHK4 in a heterologous bioassay system. Among the PBU derivatives, all the symmetric ureas/thioureas show an adventitious rooting adjuvant activity in various bioassays, confirming that this activity is strictly dependent on their chemical structure.