296242-35-8

Basic information

• Product Name: (2S,3S)-2-Hexyl-3-hydroxy-5-oxo-hexadecanoic acid benzyl ester
• Synonyms: (2S,3S)-2-Hexyl-3-hydroxy-5-oxo-hexadecanoic acid benzyl ester
• CAS NO: 296242-35-8
• Molecular Weight: 460.698
• Mol File: 296242-35-8.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: (2S,3S)-2-Hexyl-3-hydroxy-5-oxo-hexadecanoic acid benzyl ester(CAS DataBase Reference)
• NIST Chemistry Reference: (2S,3S)-2-Hexyl-3-hydroxy-5-oxo-hexadecanoic acid benzyl ester(296242-35-8)
• EPA Substance Registry System: (2S,3S)-2-Hexyl-3-hydroxy-5-oxo-hexadecanoic acid benzyl ester(296242-35-8)

Safety Data

• Hazardous Substances Data: 296242-35-8(Hazardous Substances Data)

Upstream product

• 620-05-3 iodomethylbenzene 
• 296242-42-7 (2S,3S)-2-Hexyl-3-hydroxy-5-oxo-hexadecanoic acid 
• 296242-31-4 (2S,5S,6R)-2-tert-Butyl-5-hexyl-6-(1-hydroxy-2-nitro-tridecyl)-[1,3]dioxan-4-one 
• 296242-33-6 (2S,5S,6S)-2-tert-Butyl-5-hexyl-6-{2-[(E)-hydroxyimino]-tridecyl}-[1,3]dioxan-4-one 
• 296242-41-6 (2S,4R,5S)-2-tert-Butyl-5-hexyl-6-oxo-[1,3]dioxane-4-carbaldehyde 
• 16891-99-9 1-nitrododecane 
• 296242-34-7 (2S,5S,6S)-2-tert-Butyl-5-hexyl-6-(2-oxo-tridecyl)-[1,3]dioxan-4-one 

Downstream Products

• 104872-04-0 Orlistat 
• 68711-40-0 (3S,4S)-3-hexyl-4-[(R)-2-hydroxytridecyl]-2-oxetanone 
• 296242-37-0 (2S,3S,5R)-2-Hexyl-3-hydroxy-5-triisopropylsilanyloxy-hexadecanoic acid benzyl ester 

Relevant articles and documents

Asymmetric synthesis of (-)-tetrahydrolipstatin: an anti-aldol-based strategy.

A stereoselective synthesis of (-)-tetrahydrolipstatin is described. The synthesis involves an asymmetric ester derived titanium enolate anti-aldol reaction, a nitro-aldol reaction to append the C-2' C(11) side chain, and a diastereoselective reduction of a beta-hydroxy ketone to an anti-1,3-diol functionality followed by its elaboration to (-)-tetrahydrolipstatin.