29654-01-1

Basic information

• Product Name: N-(2-iodo-4-fluorophenyl)acetamide
• Synonyms: N-(2-iodo-4-fluorophenyl)acetamide
• CAS NO: 29654-01-1
• Molecular Weight: 279.053
• Mol File: 29654-01-1.mol
• Article Data: 5

Chemical Properties

• CAS DataBase Reference: N-(2-iodo-4-fluorophenyl)acetamide(CAS DataBase Reference)
• NIST Chemistry Reference: N-(2-iodo-4-fluorophenyl)acetamide(29654-01-1)
• EPA Substance Registry System: N-(2-iodo-4-fluorophenyl)acetamide(29654-01-1)

Safety Data

• Hazardous Substances Data: 29654-01-1(Hazardous Substances Data)

Upstream product

• 351-83-7 4'-fluoroacetanilide 
• 371-40-4 4-fluoroaniline 
• 61272-76-2 4-fluoro-2-iodoaniline 
• 108-24-7 acetic anhydride 
• 75-36-5 acetyl chloride 

Downstream Products

• 1184952-89-3 1-(3-(((4-(Dimethylamino)-4-phenylcyclohexyl)methoxy)methyl)-5-fluoro-2-(triethylsilyl)-1H-indol-1-yl)ethanone 
• 399-73-5 6-fluoro-2-methylbenzo[d]thiazole 
• 397-59-1 3-fluoro-10H-phenothiazine 
• 1352745-19-7 1-(5-fluoro-2,3-diphenyl-1H-indol-1-yl)ethan-1-one 
• 1620284-77-6 N-(4-fluoro-2-((trifluoromethyl)thio)phenyl)acetamide 

Relevant articles and documents

TRANSGLUTAMINASE 2 (TG2) INHIBITORS

Described herein are compounds and pharmaceutical compositions containing such compounds which inhibit transglutaminase 2 (TG2). Also described herein are methods for using such TG2 inhibitors, alone or in combination with other compounds, for treating diseases or conditions that would benefit from TG2 inhibition.

Synthesis and optical properties of 2-functionally substituted 4,5-dihydrothieno[3,2-c]quinolines

N-Protected 4-(anilinomethyl)thiophene-2-carbaldehydes were prepared by the reaction of easily available 4-chloromethylthiophene-2-carbaldehyde with N-(2-halogenophenyl) substituted acetamides, 4-methylbenzenesulfonamides and carbamates in the presence of K2CO3 or Cs2CO3. The compounds obtained were converted to 4,5-dihydrothieno [3,2-c]quinoline-2-carbaldehydes by palladium catalyzed intramolecular cyclization in homogenous or heterogenous (Pd/C) conditions with good yields and subsequently used for preparing of 2-functionally substituted thieno [3,2-c]quinoline derivatives (nitriles, carboxamides, carboxylic acids, esters). The optical properties of 2-functionally substituted thieno[3,2-c]quinolines and 4H-thieno[3,2-c]chromenes have been studied. Moderate to high fluorescence quantum yields are observed for these compounds ranging from 0.15 to 0.87. Structure - optical properties relationships have been established for the compounds synthesized, and their prospective application as invisible ink dyes was practically demonstrated.

Substituted 4-aminocyclohexane derivatives

Substituted 4-aminocyclohexane derivatives having the formula I: [image] wherein R1-R4 are as described herein, methods for their preparation, medicinal products and pharmaceutical compositions containing these compounds and the use of substituted 4-amino