61272-76-2 Usage
Description
4-Fluoro-2-iodoaniline is an organic compound that serves as an intermediate in the synthesis of various organic chemicals. It is characterized by its clear yellow to deep yellow liquid appearance.
Uses
Used in Chemical Synthesis:
4-Fluoro-2-iodoaniline is used as an organic chemical synthesis intermediate for the production of a range of chemical compounds. Its unique structure, which includes a fluorine atom at the 4-position and an iodine atom at the 2-position on the aniline backbone, makes it a valuable building block in the creation of various pharmaceuticals, agrochemicals, and other specialty chemicals.
Used in Pharmaceutical Industry:
In the pharmaceutical industry, 4-Fluoro-2-iodoaniline is utilized as a key intermediate in the synthesis of drugs with specific therapeutic properties. Its presence in the molecular structure can influence the activity, selectivity, and pharmacokinetics of the final drug product, making it an essential component in the development of novel therapeutic agents.
Used in Agrochemical Industry:
4-Fluoro-2-iodoaniline also finds application in the agrochemical industry, where it is used as a starting material for the synthesis of various pesticides and other crop protection agents. Its unique chemical properties allow for the development of compounds with improved efficacy and selectivity, contributing to more effective and environmentally friendly agricultural practices.
Used in Dye and Pigment Industry:
In the dye and pigment industry, 4-Fluoro-2-iodoaniline is employed as a precursor for the synthesis of various organic dyes and pigments. Its distinct chemical structure contributes to the development of dyes with specific color properties and improved stability, which are essential for various applications in the textile, plastics, and printing industries.
Used in Research and Development:
4-Fluoro-2-iodoaniline is also used in research and development settings, where it serves as a versatile building block for the synthesis of novel compounds with potential applications in various fields. Its unique properties make it an attractive candidate for the development of new materials and the exploration of new chemical reactions and processes.
Check Digit Verification of cas no
The CAS Registry Mumber 61272-76-2 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 6,1,2,7 and 2 respectively; the second part has 2 digits, 7 and 6 respectively.
Calculate Digit Verification of CAS Registry Number 61272-76:
(7*6)+(6*1)+(5*2)+(4*7)+(3*2)+(2*7)+(1*6)=112
112 % 10 = 2
So 61272-76-2 is a valid CAS Registry Number.
InChI:InChI=1/C6H5FIN/c7-4-1-2-6(9)5(8)3-4/h1-3H,9H2
61272-76-2Relevant articles and documents
Au(I)-Catalyzed 6-endo-dig Cyclizations of Aromatic 1,5-Enynes to 2-(Naphthalen-2-yl)anilines Leading to Divergent Syntheses of Benzo[α]carbazole, Benzo[c,h]cinnoline and Dibenzo[i]phenanthridine Derivatives
Fu, Jiayue,Li, Bingbing,Wang, Xiugui,Liang, Qida,Peng, Xiaoshi,Yang, Lu,Wan, Tao,Wang, Xinxiu,Lin, Bin,Cheng, Maosheng,Liu, Yongxiang
supporting information, p. 46 - 52 (2021/11/20)
A gold(I)-catalyzed 6-endo-dig cyclization of aromatic 1,5-enynes was developed to synthesize 2-(naphthalen-2-yl)anilines. The functional group tolerance of this cyclization was examined systematically and a possible mechanism was proposed. The derivatization of 2-(naphthalen-2-yl)aniline was carried out to facile access to benzo[α]carbazole, benzo[c,h]cinnoline and dibenzo[i]phenanthridine derivatives in a divergent way.
A Diastereoselective Route to Benzoannelated Bridged Sultams
Klochkova, Anastasiia A.,Rassadin, Valentin A.,Sokolov, Victor V.
supporting information, p. 4484 - 4494 (2021/08/13)
A practical diastereoselective method for the synthesis of benzoannelated tri- and tetracyclic bridged sultams has been developed. The synthetic route employs widely available, substituted -iodoanilines and is based on intramolecular Michael addition followed by cycloalkylation with dihaloalkanes, or vice versa. The target compounds were isolated in good yields and the diastereoselectivity of the reaction could be easily controlled by the order of Michael addition and cycloalkylation steps.
Cu(II)-Promoted Cascade Synthesis of Fused Imidazo-Pyridine-Carbonitriles
Rakshit, Amitava,Dhara, Hirendra Nath,Alam, Tipu,Dahiya, Anjali,Patel, Bhisma K.
supporting information, p. 17504 - 17510 (2021/11/18)
A Cu(II)-promoted synthesis of an aza-fused N-heterocycle having a benz-imidazopyridine scaffold is developed via an addition-cyclization reaction followed by an Ullmann-type C-N coupling between o-iodoanilines and γ-ketodinitriles. This protocol features a broad substrate scope, giving products in 32-84% yields. The compounds show excellent photoluminescence properties having two absorption maxima in the region between 270-280 and 338-350 nm and emission maxima in the range of 502-533 nm. The HOMO-LUMO energy gap of 3.49-3.57 eV was determined using Gaussian 09 at the B3LYP/6-31G (d, p) basis set level. We also demonstrated a few postsynthetic modifications.
