29681-46-7

Basic information

• Product Name: METHYL 5-METHOXY-3-PYRIDINECARBOXYLATE, 90%
• Synonyms: METHYL 5-METHOXY-3-PYRIDINECARBOXYLATE, 90%;METHYL 5-METHOXYNICOTINATE;Methyl 5-methoxypyridine-3-carboxylate;3-Pyridinecarboxylic acid, 5-methoxy-, methyl ester;methyl 5-butoxypyridine-3-carboxylate
• CAS NO: 29681-46-7
• Molecular Formula: C₈H₉NO₃
• Molecular Weight: 167.16196
• Product Categories: Heterocyclic Compounds
• Mol File: 29681-46-7.mol
• Article Data: 8

Chemical Properties

• Melting Point: 54-59 °C
• Boiling Point: 250.891°C at 760 mmHg
• Flash Point: 110 °C
• Appearance: /
• Density: 1.156g/cm³
• Vapor Pressure: 0.021mmHg at 25°C
• Refractive Index: 1.504
• Storage Temp.: Sealed in dry,Room Temperature
• PKA: 2.39±0.10(Predicted)
• CAS DataBase Reference: METHYL 5-METHOXY-3-PYRIDINECARBOXYLATE, 90%(CAS DataBase Reference)
• NIST Chemistry Reference: METHYL 5-METHOXY-3-PYRIDINECARBOXYLATE, 90%(29681-46-7)
• EPA Substance Registry System: METHYL 5-METHOXY-3-PYRIDINECARBOXYLATE, 90%(29681-46-7)

Safety Data

• Hazard Codes: Xi
• Statements: 37/38-41
• Safety Statements: 26-39
• WGK Germany: 3
• HazardClass: IRRITANT
• Hazardous Substances Data: 29681-46-7(Hazardous Substances Data)

Usage

General Description

Methyl 5-methoxy-3-pyridinecarboxylate, 90% is a chemical compound with the molecular formula C8H9NO3 and a purity of 90%. It is a derivative of pyridine and is commonly used in the pharmaceutical and agrochemical industries. METHYL 5-METHOXY-3-PYRIDINECARBOXYLATE, 90% is known for its antimicrobial and antioxidant properties, and it is often used as an intermediate in the synthesis of various drugs and agricultural chemicals. Methyl 5-methoxy-3-pyridinecarboxylate, 90% is a versatile and valuable chemical that plays a crucial role in the development and production of a wide range of products.

InChI:InChI=1/C8H9NO3/c1-11-7-3-6(4-9-5-7)8(10)12-2/h3-5H,1-2H3

Upstream product

• 186581-53-3 diazomethane 
• 30766-22-4 methyl 5-hydroxy-3-pyridinecarboxylate 
• 138-24-9 phenyltrimethylammonium chloride 
• 109345-94-0 3-hydroxy-5-methoxypyridine 
• 20826-03-3 5-methoxypyridine-3-carboxylic acid 
• 20826-04-4 5-bromo-3-pyridinecarboxylic acid 
• 29681-44-5 5-bromo-3-pyridine carboxylic acid methyl ester 
• 107-31-3 Methyl formate 
• 850991-69-4 5-methoxy-3-pyridinylboronic acid 
• 3186-53-6 O-methyl S-p-methylphenyl thiocarbonate 
• 74-88-4 methyl iodide 

Downstream Products

• 20826-03-3 5-methoxypyridine-3-carboxylic acid 
• 1374353-52-2 1-(2-fluoro-6-methoxybenzyl)-5-methoxypiperidine-3-carboxylic acid 
• 1374353-50-0 methyl 1-(2-fluoro-6-methoxybenzyl)-5-methoxypiperidine-3-carboxylate 
• 1355730-03-8 methyl 2-(difluoromethyl)-5-methoxynicotinate 
• 1355729-95-1 methyl 4-(difluoromethyl)-5-methoxynicotinate 
• 1355729-44-0 methyl 6-(difluoromethyl)-5-methoxynicotinate 
• 937202-11-4 (5-methoxypyridin-3-yl)methanol 
• 177661-64-2 3-methoxy-5-[1-[4-(methylsulfonyl)phenyl]-4-(trifluoromethyl)-1H-imidazol-2-yl]pyridine 
• 298204-74-7 5-(methyloxy)pyridine-3-carbonitrile 

Relevant articles and documents

A predictive model for additions to: N -alkyl pyridiniums

Disclosed in this communication is a thorough study on the dearomative addition of organomagnesium nucleophiles to N-alkyl pyridinium electrophiles. The regiochemical outcomes have observable and predictable trends associated with the substituent patterns on the pyridinium electrophile. Often, the substituent effects can be either additive, giving high selectivities, or ablative, giving competing outcomes. Additionally, the nature of the organometallic nucleophilic component was also investigated for its role in the regioselective outcome. The effects of either reactive component are important to both the overall reactivity and site of nucleophilic addition. The utility of these observed trends is demonstrated in a concise, dearomative synthesis of a tricyclic compound shown to have insecticidal activity. This journal is

Nickel-catalyzed carboxylation of aryl and heteroaryl fluorosulfates using carbon dioxide

The development of efficient and practical methods to construct carboxylic acids using CO2 as a C1 synthon is of great importance. Nickel-catalyzed carboxylation of aryl fluorosulfates and heteroaryl fluorosulfates with CO2 is described, affording arene carboxylic acids with good to excellent yields under mild conditions. In addition, a one-pot phenol fluorosulfation/carboxylation is developed.

MORPHOLINE CARBOXAMIDE PROKINETICIN RECEPTOR ANTAGONISTS

The present invention is directed to morpholine carboxamide compounds which are antagonists of prokineticin receptors, in particular antagonists of prokineticin 2 receptors, and which are useful in the treatment or prevention of neurological and psychiatr