29842-94-2

Basic information

• Product Name: L-Leucine, N-[(phenylmethoxy)carbonyl]-L-phenylalanyl-, 1,1-dimethylethyl ester
• CAS NO: 29842-94-2
• Molecular Formula: C27H36N2O5
• Molecular Weight: 468.593
• Mol File: 29842-94-2.mol
• Article Data: 16

Chemical Properties

• CAS DataBase Reference: L-Leucine, N-[(phenylmethoxy)carbonyl]-L-phenylalanyl-, 1,1-dimethylethyl ester(CAS DataBase Reference)
• NIST Chemistry Reference: L-Leucine, N-[(phenylmethoxy)carbonyl]-L-phenylalanyl-, 1,1-dimethylethyl ester(29842-94-2)
• EPA Substance Registry System: L-Leucine, N-[(phenylmethoxy)carbonyl]-L-phenylalanyl-, 1,1-dimethylethyl ester(29842-94-2)

Safety Data

• Hazardous Substances Data: 29842-94-2(Hazardous Substances Data)

Upstream product

• 3397-32-8 N-(benzyloxycarbonyl)-phenylalanine-N-hydroxysuccinimide ester 
• 113304-68-0 IPAoc-Leu-O-t-Bu 
• 21691-53-2 L-leucine tert-butyl ester 
• 1161-13-3 N-Cbz-L-Phe 
• 4816-89-1 Cbz-Phe-OCH₂CONH₂ 
• 35909-92-3 N-carbobenzoxy-L-phenylalanine methyl ester 
• 2748-02-9 L-leucine tert-butyl ester hydrochloride 
• 4313-73-9 N-[N-[(phenylmethoxy)carbonyl]-L-phenylalanyl]-L-leucine 
• 75-65-0 tert-butyl alcohol 
• 80682-32-2 tert-butyl leucinate hydrotosylate 
• 60379-01-3 N-(benzyloxycarbonyl)-L-phenylalanine benzyl ester 

Downstream Products

• 2953-42-6 Z-phenylalanylleucine ethyl ester 
• 60641-89-6 N-(benzyloxycarbonyl)phenylalanylleucine benzyl ester 
• 3850-45-1 Cbz-L-Phe-L-Leu-OMe 
• 4313-73-9 N-[N-[(phenylmethoxy)carbonyl]-L-phenylalanyl]-L-leucine 
• 77426-99-4 AcOH-Gly-Gly-Phe-Leu-O-t-butyl 
• 77426-95-0 Z-Gly-Gly-Phe-Leu-O-t-butyl 
• 138850-03-0 Cbz-Leu-Leu-Phe-Leu-OtBu 
• 138850-04-1 Cbz-Val-Leu-Phe-Leu-OtBu 
• 94825-57-7 (D)Ala², Leu⁵-Enk acetate 
• 85574-41-0 Z-Tyr(Z)-(D)Ala-Gly-Phe-Leu-OBu-t 
• 88831-24-7 Z-Tyr(Z)-(D)Ala-Gly-Phe-Leu-OH 
• 111633-87-5 (S)-2-((S)-2-Benzyloxycarbonylamino-3-phenyl-propylamino)-4-methyl-pentanoic acid tert-butyl ester 
• 28635-78-1 L-phenylalanyl-L-leucine tert-butyl ester 

Relevant articles and documents

METHOD FOR PRODUCING AMIDE COMPOUND

Provided is a novel method for producing amide compounds at high stereochemical selectivities. The method according to the present invention for producing amide compounds is provided with an amidation step for reacting, in the presence of a catalyst compr

Stereocontrolled [11C]Alkylation of N-Terminal Glycine Schiff Bases To Obtain Dipeptides

The use of various quaternary ammonium salts as chiral phase-transfer catalysts allowed effective and stereoselective radiochemical [11C]alkylation to obtain functionalized dipeptides. We herein report a broadly applicable procedure for the asymmetric [11C]alkylation of dipeptides to give labeled N-terminal peptides by using different [11C]alkyl halides. Contended stereoselectivities of the reactions were observed by using 11C-labeled alkyl halides, [11C]methyl iodide and [11C]benzyl iodide, and diastereomeric ratios with different specialized catalysts of 95:5 and 90:10 were achieved, respectively. Accordingly, the straightforward synthesis of enantioenriched compounds should play a vital role in peptide-based radiopharmaceutical development and positron emission tomography imaging.

Fully enzymatic peptide synthesis using C-terminal tert-butyl ester interconversion

Chemoenzymatic peptide synthesis is potentially the most cost-efficient technology for the synthesis of short and medium-sized peptides with some important advantages. For instance, stoichiometric amounts of expensive coupling reagents are not required an