30077-74-8

Basic information

• Product Name: 3-anilino-2-<4-(benzyloxy)benzyl>acrylonitrile
• Synonyms: 3-anilino-2-<4-(benzyloxy)benzyl>acrylonitrile
• CAS NO: 30077-74-8
• Molecular Weight: 340.425
• Mol File: 30077-74-8.mol
• Article Data: 3

Chemical Properties

• CAS DataBase Reference: 3-anilino-2-<4-(benzyloxy)benzyl>acrylonitrile(CAS DataBase Reference)
• NIST Chemistry Reference: 3-anilino-2-<4-(benzyloxy)benzyl>acrylonitrile(30077-74-8)
• EPA Substance Registry System: 3-anilino-2-<4-(benzyloxy)benzyl>acrylonitrile(30077-74-8)

Safety Data

• Hazardous Substances Data: 30077-74-8(Hazardous Substances Data)

Upstream product

• 4397-53-9 p-benzyloxybenzaldehyde 
• 62-53-3 aniline 
• 116168-96-8 (Z)-2-(4-Benzyloxy-benzyl)-3-morpholin-4-yl-acrylonitrile 
• 1075-76-9 N-cyanoethylaniline 

Downstream Products

• 30077-67-9 2,4-diamino-5-(4-hydroxybenzyl)pyrimidine 
• 49873-11-2 5-(4-benzyloxy-benzyl)-pyrimidine-2,4-diamine 

Relevant articles and documents

Synthesis and antimycobacterial effects of some lipophilic substituted 2,4-diamino-5-benzylpyrimidines

2,4-Diamino-5-benzylpyrimidines 1-23 with lipophilic substitution in the benzylic moiety were synthesized by the morpholino-anilino-procedure. Their effects against various mycobacteria were verified by MIC (minimum inhibitory concentration) in whole cells and I50-measurements in whole cell and cell-free systems. Especially the substances 7-12 are strong inhibitors of some atypical mycobacterial strains which are sometimes associated with tuberculosis in the elderly and with AIDS. They might be promising candidates for therapy.

Preparation of β-anilino-α-benzylacrylonitriles

Compounds comprising selected N-substituted β-amino-α-benzyl-acrylonitriles and methods of preparing said compounds substantially free from the corresponding bensalacrylonitrile. The compounds are useful as intermediates in the preparation of antibacterial and antimalerial agents.