302567-98-2

Basic information

• Product Name: Carbamic acid, (4-methoxyphenyl)-, 9H-fluoren-9-ylmethyl ester (9CI)
• Synonyms: Carbamic acid, (4-methoxyphenyl)-, 9H-fluoren-9-ylmethyl ester (9CI)
• CAS NO: 302567-98-2
• Molecular Formula: C22H19NO3
• Molecular Weight: 345.39116
• Product Categories: FMOC
• Mol File: 302567-98-2.mol
• Article Data: 3

Chemical Properties

• Appearance: /
• CAS DataBase Reference: Carbamic acid, (4-methoxyphenyl)-, 9H-fluoren-9-ylmethyl ester (9CI)(CAS DataBase Reference)
• NIST Chemistry Reference: Carbamic acid, (4-methoxyphenyl)-, 9H-fluoren-9-ylmethyl ester (9CI)(302567-98-2)
• EPA Substance Registry System: Carbamic acid, (4-methoxyphenyl)-, 9H-fluoren-9-ylmethyl ester (9CI)(302567-98-2)

Safety Data

• Hazardous Substances Data: 302567-98-2(Hazardous Substances Data)

Upstream product

• 28920-43-6 (fluorenylmethoxy)carbonyl chloride 
• 104-94-9 4-methoxy-aniline 
• 102774-86-7 9-fluorenylmethyl N-succinimidyl carbonate 

Relevant articles and documents

A greener, efficient and catalyst-free ultrasonic-assisted protocol for the n-fmoc protection of amines

A simple, eco-sustainable method for the N-(9-fluorenylmethoxycarbonyl) (N-Fmoc) protection of various structurally amines under ultrasonic irradiation is reported. The corresponding N-Fmoc derivatives were obtained in good to excellent yields within short reaction time. The reaction proceeds without the formation of any side product. Mildness, efficiency and easier work are the main advantages of this new protocol.

A rate enhancement of tert-butoxycarbonylation of aromatic amines with Boc2O in alcoholic solvents

A rate enhancement of tert-butoxycarbonylation of aromatic amines by Boc2O in alcohols compared to aprotic solvents was demonstrated. Kinetic analysis by NMR suggested that the reaction in CD3OD was faster than in CDCl3 by a factor of 70. Reactions between Boc2O and various aliphatic and aromatic amines in ethanol provided the N-Boc derivatives in good to excellent yields in short reaction times.