303730-26-9

Basic information

• Product Name: DIETHYL BIPHENYL 3,3'-DICARBOXYLATE
• Synonyms: DIETHYL BIPHENYL 3,3'-DICARBOXYLATE
• CAS NO: 303730-26-9
• Molecular Formula: C18H18O4
• Molecular Weight: 298.33
• Mol File: 303730-26-9.mol
• Article Data: 11

Chemical Properties

• Melting Point: 68-69 °C
• Boiling Point: 446.4°C at 760 mmHg
• Flash Point: 224.4°C
• Appearance: /
• Density: 1.132g/cm³
• Vapor Pressure: 3.66E-08mmHg at 25°C
• Refractive Index: 1.547
• CAS DataBase Reference: DIETHYL BIPHENYL 3,3'-DICARBOXYLATE(CAS DataBase Reference)
• NIST Chemistry Reference: DIETHYL BIPHENYL 3,3'-DICARBOXYLATE(303730-26-9)
• EPA Substance Registry System: DIETHYL BIPHENYL 3,3'-DICARBOXYLATE(303730-26-9)

Safety Data

• Hazardous Substances Data: 303730-26-9(Hazardous Substances Data)

Usage

InChI:InChI=1/C18H18O4/c1-3-21-17(19)15-9-5-7-13(11-15)14-8-6-10-16(12-14)18(20)22-4-2/h5-12H,3-4H2,1-2H3

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Relevant articles and documents

Pd-catalyzed oxidative homocoupling of arylboronic acids in WEPA: A sustainable access to symmetrical biaryls under added base and ligand-free ambient conditions

Symmetrical and unsymmetrical biaryls comprises a diverse class of biologically eloquent organic compounds. We herein report, a quick and eco-friendly protocol for the synthesis of biaryls by an oxidative (aerobic) homocoupling of arylboronic acids (ABAs) using Pd(OAc)2 in water extract of pomogranate ash (WEPA) as an efficient agro-waste(bio)-derived aqueous (basic) media. The reactions were executed at ambient aerobic conditions in the absence of external base and ligand to result symmetrical biaryls in excellent yields. The use of renewable media with an effective exploitation of waste, short reaction times, excellent yields of products, easy separation of the products, unnecessating the external base, oxidant, ligand or volatile organic solvents and ambient reaction conditions are the vital insights of the present protocol.

Cobalt-xantphos-catalyzed, LiCl-mediated preparation of arylzinc reagents from aryl iodides, bromides, and chlorides

A cobalt-Xantphos-catalyzed, LiCl-mediated system has been developed for the direct and expedient preparation of arylzinc reagents in THF from the corresponding aryl iodides, bromides, and chlorides. Owing to the use of THF as a versatile solvent, the thus-formed arylzinc reagents displayed a high degree of compatibility with a variety of conventional as well as newly emerging metal-catalyzed cross-coupling reactions.

Efficient cobalt-catalyzed formation of unsymmetrical biaryl compounds and its application in the synthesis of a sartan intermediate

(Chemical Equation Presented) No prior preparation of the organometallic reagent is required in a cobalt-catalyzed coupling of two different aryl halides under mild conditions (see scheme). A broad spectrum of valuable biaryl compounds can be prepared in this way. Not only may a variety of reactive substituents be present, but heteroaryl halides and aryl triflates are also suitable substrates. DMF = N,N-dimethylformamide, FG = functional group.