305818-39-7 Usage
Description
(4aS,6aR,6bS,12aS,14aR,14bR,Z)-Methyl 11-(hydroxyMethylene)-2,2,6a,6b,9,9,12a-heptaMethyl-10,14-dioxo-1,2,3,4,4a,5,6,6a,6b,7,8,8a,9,10,11,12,12a,14,14a,14b-icosahydropicene-4a-carboxylate is a complex organic compound with a long chain of carbon atoms, featuring several methyl and carbonyl (C=O) functional groups, as well as a hydroxyMethylene (-CH2OH) group. It is likely a derivative of picene, a hydrocarbon compound, and contains a carboxylate group. The lengthy and intricate structure of this chemical suggests potential applications in various fields such as organic chemistry, pharmaceuticals, and materials science.
Uses
Used in Pharmaceutical Industry:
(4aS,6aR,6bS,12aS,14aR,14bR,Z)-Methyl 11-(hydroxyMethylene)-2,2,6a,6b,9,9,12a-heptaMethyl-10,14-dioxo-1,2,3,4,4a,5,6,6a,6b,7,8,8a,9,10,11,12,12a,14,14a,14b-icosahydropicene-4a-carboxylate is used as a potential pharmaceutical compound for its complex structure that may offer novel therapeutic properties. The presence of various functional groups could allow for interactions with biological targets, making it a candidate for drug development.
Used in Organic Chemistry Research:
In the field of organic chemistry, this compound is used as a subject of study for its unique structural features. It can be employed in the synthesis of other complex organic molecules, potentially leading to the discovery of new chemical reactions and mechanisms.
Used in Materials Science:
(4aS,6aR,6bS,12aS,14aR,14bR,Z)-Methyl 11-(hydroxyMethylene)-2,2,6a,6b,9,9,12a-heptaMethyl-10,14-dioxo-1,2,3,4,4a,5,6,6a,6b,7,8,8a,9,10,11,12,12a,14,14a,14b-icosahydropicene-4a-carboxylate's structural complexity and functional groups may also make it a candidate for use in the development of new materials with specific properties. It could be utilized in the creation of advanced materials for various applications, such as in electronics, coatings, or as components in composite materials.
Check Digit Verification of cas no
The CAS Registry Mumber 305818-39-7 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 3,0,5,8,1 and 8 respectively; the second part has 2 digits, 3 and 9 respectively.
Calculate Digit Verification of CAS Registry Number 305818-39:
(8*3)+(7*0)+(6*5)+(5*8)+(4*1)+(3*8)+(2*3)+(1*9)=137
137 % 10 = 7
So 305818-39-7 is a valid CAS Registry Number.
305818-39-7Relevant articles and documents
Synthetic oleanane and ursane triterpenoids with modified rings A and C: A series of highly active inhibitors of nitric oxide production in mouse macrophages
Honda,Rounds,Bore,Finlay,Favaloro Jr.,Suh,Wang,Sporn,Gribble
, p. 4233 - 4246 (2000)
We have designed and synthesized 16 new olean- and urs-1-en-3-one triterpenoids with various modified rings C as potential antiinflammatory and cancer chemopreventive agents and evaluated their inhibitory activities against production of nitric oxide induced by interferon-γ in mouse macrophages. This investigation revealed that 9(11)-en-12-one and 12-en-11-one functionalities in ring C increase the potency by about 2-10 times compared with the original 12-ene. Subsequently, we have designed and synthesized novel olean- and urs-1-en-3-one derivatives with nitrile and carboxyl groups at C-2 in ring A and with 9(11)-en-12-one and 12-en-11-one functionalities in ring C. Among them, we have found that methyl 2-cyano-3, 12-dioxooleana-1,9(11)-dien-28-oate (25), 2-cyano-3,12-dioxooleana-1,9(11)-dien-28-oic acid (CDDO) (26), and methyl 2-carboxy-3,12-dioxooleana-1,9(11)-dien-28-oate (29) have extremely high potency (IC50 = 0.1 nM level). Their potency is similar to that of dexamethasone although they do not act through the glucocorticoid receptor. Overall, the combination of modified rings A and C increases the potency by about 10 000 times compared with the lead compound, 3-oxooleana-1,12-dien-28-oic acid (8) (IC50 = 1 μM level). The selected oleanane triterpenoid, CDDO (26), was found to be a potent, multifunctional agent in various in vitro assays and to show antiinflammatory activity against thioglycollate-interferon-γ-induced mouse peritonitis.