30834-42-5

Basic information

• Product Name: Spiro[5.5]undec-1-en-3-one
• Synonyms: Spiro[5.5]undec-1-en-3-one
• CAS NO: 30834-42-5
• Molecular Formula: C₁₁H₁₆O
• Molecular Weight: 164.24414
• Mol File: 30834-42-5.mol
• Article Data: 11

Chemical Properties

• Boiling Point: 279.4°Cat760mmHg
• Flash Point: 133.9°C
• Appearance: /
• Density: 1g/cm³
• Vapor Pressure: 0.00404mmHg at 25°C
• Refractive Index: 1.509
• CAS DataBase Reference: Spiro[5.5]undec-1-en-3-one(CAS DataBase Reference)
• NIST Chemistry Reference: Spiro[5.5]undec-1-en-3-one(30834-42-5)
• EPA Substance Registry System: Spiro[5.5]undec-1-en-3-one(30834-42-5)

Safety Data

• Hazardous Substances Data: 30834-42-5(Hazardous Substances Data)

Usage

General Description

Spiro[5.5]undec-1-en-3-one is a chemical compound with a unique spirocyclic structure. It is a ketone with a 10-membered carbon ring and a double bond at the 1 position. Spiro[5.5]undec-1-en-3-one is commonly used in organic synthesis and medicinal chemistry as a building block for the creation of more complex molecules. Its spirocyclic nature makes it a valuable scaffold for the development of pharmaceuticals and bioactive compounds. Additionally, its structural features give it distinct chemical and physical properties that make it useful in a variety of applications, including in the fragrance and flavor industry. Overall, Spiro[5.5]undec-1-en-3-one is a versatile and important compound in the field of organic chemistry.

InChI:InChI=1/C11H16O/c12-10-4-8-11(9-5-10)6-2-1-3-7-11/h4,8H,1-3,5-7,9H2

Upstream product

• 6815-55-0 1-(cyclohexylidenemethyl)pyrrolidine 
• 78-94-4 methyl vinyl ketone 
• 64244-35-5 Cyclohexylidenemethyl-[1-phenyl-meth-(E)-ylidene]-amine 
• 108-94-1 cyclohexanone 
• 1192-37-6 methylenecyclohexane 
• 2043-61-0 cyclohexanecarbaldehyde 
• 53282-55-6 (trimethylsiloxymethylidene)cyclohexane 
• 77419-46-6 C₁₀H₁₆O 
• 152568-20-2 1-Vinyl-spiro[3.5]nonan-1-ol 
• 30834-43-6 1-Formyl-1-(3-oxobutyl)cyclohexane 

Downstream Products

• 4729-21-9 dispiro<5,5>undeca-1,4-dien-3-one 
• 1890-25-1 spiro[5.5]undecan-3-one 
• 122723-75-5 4-Methoxy-benzoic acid 3-oxo-spiro[5.5]undec-4-en-2-yl ester 
• 2126-94-5 spiro[5.5]undecan-3-amine hydrochloride 
• 18244-47-8 spiro[5.5]undecane-3-carboxylic acid 
• 122723-64-2 Benzoic acid 3-oxo-spiro[5.5]undec-4-en-2-yl ester 
• 122723-72-2 Dichloro-acetic acid 3-oxo-spiro[5.5]undec-4-en-2-yl ester 

Relevant articles and documents

Radical Carbonyl Umpolung Arylation via Dual Nickel Catalysis

The formation of carbon-carbon bonds lies at the heart of synthetic organic chemistry and is widely applied to construct complex drugs, polymers, and materials. Despite its importance, catalytic carbonyl arylation remains comparatively underdeveloped, due

Free-radical carbo-oximation of olefins and subsequent radical-ionic cascades

A sequential carbo-formylation cascade has been developed, involving a free-radical carbo-oximation process, followed by the hydrolysis of the oxime ether. For this purpose, we designed a new SEM O-protected sulfonyl oxime, which enable both rapid radical addition and hydrolysis under mild conditions. The resulting aldehyde-esters were then engaged in various nucleophilic cascades, such as Sakurai allylations or domino-Mukaiyama aldol condensation/ lactonizations. Addition of an amine and TMSCN similarly led after Strecker reaction/lactamization to α-cyano-piperidinones in good overall yield. Finally, a Pictet-Spengler/lactamization sequence was devised, which open a new entry toward the tricyclic core of eburnan alkaloids.

SPIRO COMPOUNDS AND PHARMACEUTICAL USE THEREOF

The Spiro compound represented by the following general formula [Ia], its pharmaceutically acceptable salt or a solvate thereof