309927-66-0

Basic information

• Product Name: 4-[5,6-dimethoxy-1-(4-methylphenylsulfonyl)-3-phenyl-1H-2-indolyl]-2-butanone
• Synonyms: 4-[5,6-dimethoxy-1-(4-methylphenylsulfonyl)-3-phenyl-1H-2-indolyl]-2-butanone
• CAS NO: 309927-66-0
• Molecular Weight: 477.581
• Mol File: 309927-66-0.mol
• Article Data: 3

Chemical Properties

• CAS DataBase Reference: 4-[5,6-dimethoxy-1-(4-methylphenylsulfonyl)-3-phenyl-1H-2-indolyl]-2-butanone(CAS DataBase Reference)
• NIST Chemistry Reference: 4-[5,6-dimethoxy-1-(4-methylphenylsulfonyl)-3-phenyl-1H-2-indolyl]-2-butanone(309927-66-0)
• EPA Substance Registry System: 4-[5,6-dimethoxy-1-(4-methylphenylsulfonyl)-3-phenyl-1H-2-indolyl]-2-butanone(309927-66-0)

Safety Data

• Hazardous Substances Data: 309927-66-0(Hazardous Substances Data)

Upstream product

• 91-16-7 1,2-dimethoxybenzene 
• 4038-14-6 3,4-dimethoxybenzophenone 
• 886499-20-3 N-(2-formyl-4,5-dimethoxyphenyl)-4-methylbenzenesulfonamide 
• 534-22-5 2-methylfuran 
• 340696-16-4 N-(4,5-dimethoxy-2-(hydroxy(phenyl)methyl)phenyl)-4-methylbenzenesulfonamide 
• 871563-17-6 N-(2-hydroxymethyl-4,5-dimethoxyphenyl)-4-methylbenzenesulfonamide 
• 71089-34-4 methyl 4,5-dimethoxy-2-(p-toluenesulfonamido)benzoate 
• 26759-46-6 methyl 2-amino-4,5-dimethoxybenzoate 
• 5653-40-7 2-Amino-4,5-dimethoxybenzoic acid 
• 98-88-4 benzoyl chloride 
• 39996-22-0 (2-amino-4,5-dimethoxyphenyl)-(phenyl)methanone 
• 255896-36-7 (4,5-dimethoxy-2-nitrophenyl)-(phenyl)methanone 
• 309927-64-8 2-benzoyl-4,5-dimethoxy-1-(4-methylphenylsulfonamido)benzene 
• 309927-65-9 4-methyl-N-{4,5-dimethoxy-2-[(5-methylfuran-2-yl)(phenyl)methyl]phenyl}benzenesulfonamide 

Relevant articles and documents

Broensted acid-catalyzed one-pot synthesis of indoles from o-aminobenzyl alcohols and furans

Broensted acid-catalyzed one-pot synthesis of indoles from o-aminobenzyl alcohols and furans has been developed. This method operates via the in situ formation of aminobenzylfuran, followed by its recyclization into the indole core. The method proved to be efficient for substrates possessing different functional groups, including -OMe, -CO2Cy, and -Br. The resulting indoles can easily be transformed into diverse scaffolds, including 2,3- and 1,2-fused indoles, and indoles possessing an α,β-unsaturated ketone moiety at the C-2 position.

Furan ring opening - Indole ring closure: A new modification of the Reissert reaction for indole synthesis

A new modification of the Reissert reaction is reported. On treatment of 2-tosylaminobenzylfurans with ethanolic HCl, some indole derivatives have been obtained. The furan ring served as the origin of a carbonyl group in this reaction.