886499-20-3

Basic information

• Product Name: N-(2-FORMYL-4,5-DIMETHOXY-PHENYL)-4-METHYL-BENZENESULFONAMIDE
• Synonyms: N-(2-FORMYL-4,5-DIMETHOXY-PHENYL)-4-METHYL-BENZENESULFONAMIDE
• CAS NO: 886499-20-3
• Molecular Formula: C₁₆H₁₇NO₅S
• Molecular Weight: 335.37
• Mol File: 886499-20-3.mol
• Article Data: 5

Chemical Properties

• Appearance: /
• CAS DataBase Reference: N-(2-FORMYL-4,5-DIMETHOXY-PHENYL)-4-METHYL-BENZENESULFONAMIDE(CAS DataBase Reference)
• NIST Chemistry Reference: N-(2-FORMYL-4,5-DIMETHOXY-PHENYL)-4-METHYL-BENZENESULFONAMIDE(886499-20-3)
• EPA Substance Registry System: N-(2-FORMYL-4,5-DIMETHOXY-PHENYL)-4-METHYL-BENZENESULFONAMIDE(886499-20-3)

Safety Data

• Hazardous Substances Data: 886499-20-3(Hazardous Substances Data)

Upstream product

• 98-59-9 p-toluenesulfonyl chloride 
• 22608-87-3 2-amino-4,5-dimethoxybenzaldehyde 
• 20357-25-9 6-nitroveratraldehyde 
• 120-14-9 3,4-dimethoxy-benzaldehyde 
• 1016-58-6 6-nitroveratryl alcohol 
• 188174-23-4 (2-amino-4,5-dimethoxyphenyl)methanol 
• 871563-17-6 N-(2-hydroxymethyl-4,5-dimethoxyphenyl)-4-methylbenzenesulfonamide 
• 71089-34-4 methyl 4,5-dimethoxy-2-(p-toluenesulfonamido)benzoate 
• 26759-46-6 methyl 2-amino-4,5-dimethoxybenzoate 
• 5653-40-7 2-Amino-4,5-dimethoxybenzoic acid 

Downstream Products

• 340696-16-4 N-(4,5-dimethoxy-2-(hydroxy(phenyl)methyl)phenyl)-4-methylbenzenesulfonamide 
• 309927-66-0 4-[5,6-dimethoxy-1-(4-methylphenylsulfonyl)-3-phenyl-1H-2-indolyl]-2-butanone 
• 1242061-60-4 C₂₉H₃₂N₂O₄S 
• 1439383-89-7 7,8-dimethoxy-1-tosyl-1H-benzo[b]azepin-3(2H)-one 
• 1439384-22-1 N-(2-Formyl-4,5-dimethoxyphenyl)-4-methyl-N-(prop-2-yn-1-yl)benzenesulfonamide 

Relevant articles and documents

Synthesis of Azepino[1,2-a]indole-10-amines via [6+1] Annulation of Ynenitriles with Reformatsky Reagent

Lewis acid-catalyzed [6+1] annulation reactions of 2-cyano-1-propargyl- and 2-alkynyl-1-cyanomethyl-indoles with Reformatsky reagent are described. 8-Aryl, 8-alkyl-, 8-hetaryl-, 9-aryl, and 9-alkyl-azepino[1,2-a]indole amines were obtained through a 7-endo-mode cyclization of the β-aminoacrylate intermediates. The antiproliferative activity of the azepino[1,2-a]indoles analogs against the HCT-116 cells were also examined.

Diastereoselective construction of highly functionalized tetrahydroquinolinoisoxazole scaffolds via intramolecular nitrone cycloaddition

A novel strategy towards the construction of highly diversified tetrahydroquinolinoisoxazole frameworks with high diastereoselectivity via intramolecular 1,3-dipolar nitrone cycloaddition reaction is described for the first time. All the synthesized tetrahydroquinolinoisoxazoles are new and obtained in excellent yields under catalyst free condition.

Broensted acid-catalyzed one-pot synthesis of indoles from o-aminobenzyl alcohols and furans

Broensted acid-catalyzed one-pot synthesis of indoles from o-aminobenzyl alcohols and furans has been developed. This method operates via the in situ formation of aminobenzylfuran, followed by its recyclization into the indole core. The method proved to be efficient for substrates possessing different functional groups, including -OMe, -CO2Cy, and -Br. The resulting indoles can easily be transformed into diverse scaffolds, including 2,3- and 1,2-fused indoles, and indoles possessing an α,β-unsaturated ketone moiety at the C-2 position.