188174-23-4

Basic information

• Product Name: (2-amino-4,5-dimethoxyphenyl)methanol
• Synonyms: (2-amino-4,5-dimethoxyphenyl)methanol
• CAS NO: 188174-23-4
• Molecular Weight: 183.207
• Mol File: 188174-23-4.mol
• Article Data: 6

Chemical Properties

• CAS DataBase Reference: (2-amino-4,5-dimethoxyphenyl)methanol(CAS DataBase Reference)
• NIST Chemistry Reference: (2-amino-4,5-dimethoxyphenyl)methanol(188174-23-4)
• EPA Substance Registry System: (2-amino-4,5-dimethoxyphenyl)methanol(188174-23-4)

Safety Data

• Hazardous Substances Data: 188174-23-4(Hazardous Substances Data)

Usage

General Description

(2-amino-4,5-dimethoxyphenyl)methanol is a chemical compound that belongs to the class of phenols and phenyls, and it consists of a phenyl ring with two methoxy groups and an amino group attached to it. It is derived from the parent compound methanol and is used in the synthesis of various pharmaceuticals and organic compounds. This chemical compound has potential applications in the field of medicinal chemistry, especially in the development of new drugs and pharmacological agents. Its structural features and functional groups make it a versatile building block for the synthesis of biologically active molecules. Additionally, it may have physiological effects and interactions with biological systems that warrant further investigation.

Upstream product

• 1016-58-6 6-nitroveratryl alcohol 
• 26759-46-6 methyl 2-amino-4,5-dimethoxybenzoate 
• 20357-25-9 6-nitroveratraldehyde 

Downstream Products

• 57179-07-4 6,7-dimethoxy-2-phenylquinoline 
• 886499-20-3 N-(2-formyl-4,5-dimethoxyphenyl)-4-methylbenzenesulfonamide 
• 871563-17-6 N-(2-hydroxymethyl-4,5-dimethoxyphenyl)-4-methylbenzenesulfonamide 
• 22608-87-3 2-amino-4,5-dimethoxybenzaldehyde 
• 197525-04-5 5,6-dimethoxy-2,2-diphenyl-1-(4-nitrophenyl)-1,2-dihydroazeto[2,1-b]quinazoline 

Relevant articles and documents

Iron-catalyzed cascade reaction of 2-aminobenzyl alcohols with benzylamines: Synthesis of quinazolines by trapping of ammonia

A novel approach to construct 2-aryl/heteroaryl quinazolines was developed through an iron-catalyzed cascade reaction of 2-aminobenzyl alcohols with benzylamines under aerobic oxidative conditions. The reaction proceeds via the formation of N-benzylideneb

Synthesis of polysubstituted cyclopenta[b]indoles via relay gold(i)/Bronsted acid catalysis

An efficient relay catalytic process involving Au(i)/Bronsted acid to access various polysubstituted cyclopentannulated indoles from easily accessible 1-(2-aminophenyl)prop-2-ynols and readily available 1,3-dicarbonyls has been developed. In an unprecedented event, the intermediate 2-indolylmethyl cations undergo the cation-Ene reaction with various 1,3-dicarbonyls followed by an intramolecular Friedel-Crafts-type reaction generating functionalized cyclopenta[b]indoles. This journal is

COMPOUND

There is provided a compound having Formula (I), wherein each of R1, R2, R3, R4, R5, R6, R7, R8 and R9 are independently selected from (a) H, (b) R13, -OC(R13)3, -OCH(R13)2, -OCH2R13, -C(R13)3, -CH(R13)2, or -CH2R13 wherein R13 is a halogen; (c) -CN; (d) optionally substituted alkyl, (e) optionally substituted heteroalkyl; (f) optionally substituted aryl; (g) optionally substituted heteroaryl; (h) optionally substituted arylalkyl; (i) optionally substituted heteroarylalkyl; (j) hydroxy; (k) alkoxy; (I) aryloxy; (m) -SO2-alkyl; and (n) -N(R14)C(O)R15, wherein R14 and R15 are independently selected from H and hydrocarbyl, wherein the optional substituents of (d) (e) (T) (h) and (i) are selected from the group consisting of: C1-6 alkyl, halo, cyano, nitro, haloalkyl, hydroxy, C1-6 alkoxy, carboxy, carboxyalkyl, carboxamide, mercapto, amino, alkylamino, dialkylamino, sulfonyl, sulfonamido, aryl and heteroaryl; wherein n and p are independently selected from 0 and 1; X is an optional group selected from O, S, S=O, S(=O)2, C=O, S(=O)2NR16, C=ONR17, NR18, in which R16, R17, and R18 are independently selected from H and hydrocarbyl, R10 is selected from H and hydrocarbyl, R11 is selected from CR19R20 and C=O, in which R19 and R20 are independently selected from H and hydrocarbyl, R12 is selected from a substituted five or six membered carbon rings optionally containing one or more hetero atoms selected from N, S, and O and optionally having fused thereto a further ring, and wherein the one or more substituents are selected from hydrocarbyl groups.