3106-60-3

Basic information

• Product Name: 1-methylpyridin-1-ium-3-carboxamide
• Synonyms: 1-Methylnicotinamide;1-methylpyridin-1-ium-3-carboxamide;N(1)-methylnicotinamide;1-Methyl-3-(aminocarbonyl)pyridine-1-ium;1-Methyl-3-carbamoylpyridinium;3-Carbamoyl-1-methylpyridinium;Trigonellinamide;Trigonelline amide
• CAS NO: 3106-60-3
• Molecular Formula: C₇H₉N₂O
• Molecular Weight: 0
• Mol File: 3106-60-3.mol
• Article Data: 11

Chemical Properties

• Boiling Point: °Cat760mmHg
• Flash Point: °C
• Appearance: /
• Density: g/cm³
• Vapor Pressure: 0mmHg at 25°C
• Refractive Index: 1.554
• CAS DataBase Reference: 1-methylpyridin-1-ium-3-carboxamide(CAS DataBase Reference)
• NIST Chemistry Reference: 1-methylpyridin-1-ium-3-carboxamide(3106-60-3)
• EPA Substance Registry System: 1-methylpyridin-1-ium-3-carboxamide(3106-60-3)

Safety Data

• Hazardous Substances Data: 3106-60-3(Hazardous Substances Data)

Usage

Description

1-methylpyridin-1-ium-3-carboxamide is a pyridinium ion that consists of nicotinamide with a methyl group attached at the 1-position. It is an organic compound with potential applications in various industries due to its unique chemical properties.

Uses

Used in Pharmaceutical Industry:
1-methylpyridin-1-ium-3-carboxamide is used as a pharmaceutical compound for its potential therapeutic applications. Its unique structure allows it to interact with specific biological targets, making it a promising candidate for the development of new drugs.
Used in Chemical Synthesis:
1-methylpyridin-1-ium-3-carboxamide can be used as a building block or intermediate in the synthesis of more complex organic molecules. Its presence in the molecule can influence the reactivity and selectivity of chemical reactions, making it a valuable component in the synthesis of various compounds.
Used in Material Science:
Due to its unique chemical structure, 1-methylpyridin-1-ium-3-carboxamide may have potential applications in the development of new materials with specific properties. It could be used in the design of novel polymers, catalysts, or other advanced materials with tailored characteristics for various applications.
Used in Analytical Chemistry:
1-methylpyridin-1-ium-3-carboxamide can be employed as a reagent or reference compound in analytical chemistry. Its distinct chemical properties may make it useful for the detection, quantification, or separation of other compounds in complex mixtures.

InChI:InChI=1/C7H10N2O/c1-9-4-2-3-6(5-9)7(8)10/h2-4H,5H2,1H3,(H2,8,10)

Upstream product

• 98-92-0 nicotinamide 
• 15519-60-5 S-adenosyl-L-methionine 
• 74-88-4 methyl iodide 
• 485-80-3 S-adenosyl-L-methionine 
• 17750-23-1 1-methyl-1,4-dihydronicotinamide 
• 13367-81-2 10-methylacridinium cation 
• 14031-35-7 S-Adenosyl-L-methionine 
• 42986-37-8 C₇H₉N₂O 
• 94887-39-5 6,7,8,9-tetrahydro-2,3,12,13-tetramethyldipyrido<1,2-a:2'.1'-c><1,4>diazocinediium dibromide 
• 19432-60-1 4-cyano-1,4-dihydro-N-methylpyridine-3-carboxamide 
• 2139-03-9 Δ¹-pyrroline-2-carboxylic acid 

Downstream Products

• 769-49-3 1-methyl-1,4-dihydro-4-oxo-3-pyridinecarboxamide 
• 701-44-0 1-methyl-2-pyridone-5-carboxamide 
• 17750-23-1 1-methyl-1,4-dihydronicotinamide 

Relevant articles and documents

Development of a Suicide Inhibition-Based Protein Labeling Strategy for Nicotinamide N-Methyltransferase

Nicotinamide N-methyltransferase (NNMT) catalyzes the S-adenosyl-l-methionine-dependent methylation of nicotinamide to form N-methylnicotinamide. This enzyme detoxifies xenobiotics and regulates NAD+ biosynthesis. Additionally, NNMT is overexpressed in various cancers. Herein, we describe the first NNMT-targeted suicide substrates. These compounds, which include 4-chloropyridine and 4-chloronicotinamide, exploit the broad substrate scope of NNMT; methylation of the pyridine nitrogen enhances the electrophilicity of the C4 position, thereby promoting an aromatic nucleophilic substitution by C159, a noncatalytic cysteine. On the basis of this activity, we developed a suicide inhibition-based protein labeling strategy using an alkyne-substituted 4-chloropyridine that selectively labels NNMT in vitro and in cells. In total, this study describes the first NNMT-directed activity-based probes.

MASS SPECTROMETRY OF NITROGEN HETEROCYCLES. 2. CORRELATION OF MASS SPECTROMETRIC FRAGMENTATION PROCESSES AND CHEMICAL AROMATIZATION REACTIONS OF DIHYDROAZINES

The results of mass spectrometric studies of aromatization processes of dihydroazines have been compared with experimental data relative to their chemical oxidation.The results of electron impact induced ionization of dihydroazines can be correlated direc

A classical but new kinetic equation for hydride transfer reactions

A classical but new kinetic equation to estimate activation energies of various hydride transfer reactions was developed according to transition state theory using the Morse-type free energy curves of hydride donors to release a hydride anion and hydride acceptors to capture a hydride anion and by which the activation energies of 187 typical hydride self-exchange reactions and more than thirty thousand hydride cross transfer reactions in acetonitrile were safely estimated in this work. Since the development of the kinetic equation is only on the basis of the related chemical bond changes of the hydride transfer reactants, the kinetic equation should be also suitable for proton transfer reactions, hydrogen atom transfer reactions and all the other chemical reactions involved with breaking and formation of chemical bonds. One of the most important contributions of this work is to have achieved the perfect unity of the kinetic equation and thermodynamic equation for hydride transfer reactions. The Royal Society of Chemistry.