3117-38-2

Basic information

• Product Name: phenoxy(phenyl)acetic acid
• Synonyms: 2-phenoxy-2-phenylacetic acid; benzeneacetic acid, alpha-phenoxy-; Phenoxy(phenyl)acetic acid
• CAS NO: 3117-38-2
• Molecular Formula: C₁₄H₁₂O₃
• Molecular Weight: 228.2433
• Mol File: 3117-38-2.mol
• Article Data: 4

Chemical Properties

• Boiling Point: 365.8°C at 760 mmHg
• Flash Point: 138.5°C
• Density: 1.226g/cm³
• Vapor Pressure: 5.4E-06mmHg at 25°C
• Refractive Index: 1.599
• CAS DataBase Reference: phenoxy(phenyl)acetic acid(CAS DataBase Reference)
• NIST Chemistry Reference: phenoxy(phenyl)acetic acid(3117-38-2)
• EPA Substance Registry System: phenoxy(phenyl)acetic acid(3117-38-2)

Safety Data

• Hazardous Substances Data: 3117-38-2(Hazardous Substances Data)

Usage

General Description

Phenoxy(phenyl)acetic acid is a chemical compound with the molecular formula C14H12O3. It is a white solid, slightly soluble in water, and is commonly used as a precursor in the synthesis of various pharmaceuticals, such as diuretics and antihistamines. Phenoxy(phenyl)acetic acid is also used in the production of dyes and perfumes, and as a starting material for the synthesis of other organic compounds. It has potential applications in the chemical industry as a building block in the synthesis of various organic compounds. Additionally, it has been studied for its potential biological and pharmacological properties, including anti-inflammatory and antioxidant effects.

Upstream product

• 108-95-2 phenol 
• 2882-19-1 ethyl 2-phenyl-2-bromoacetate 
• 4870-65-9 2-bromophenylacetic acid 
• 19078-72-9 bromo(phenyl)acetyl chloride 
• 37167-62-7 bromo-phenyl-acetic acid methyl ester 
• 10606-73-2 ethyl 2-chloro-2-phenylacetate 
• 100-67-4 potassium phenolate 
• 256399-59-4 ethyl 2-phenoxy-2-phenylethanoate 

Downstream Products

• 88-89-1 2,4,6-Trinitrophenol 
• 100-52-7 benzaldehyde 
• 93-99-2 benzoic acid phenyl ester 
• 958029-28-2 (–)-methyl 2-phenoxy-2-phenylacetate 
• 71621-33-5 2-(α-phenoxy-benzyl)-morpholine hydrochloride 
• 93852-38-1 2-Chloro-N-(2-hydroxy-3-phenoxy-3-phenyl-propyl)-acetamide 
• 93886-29-4 6-(Phenoxy-phenyl-methyl)-morpholin-3-one 
• 71621-12-0 2-hydroxy-3-phenyl-3-phenoxy-propylamine 
• 133534-42-6 2-hydroxy-3-phenoxy-3-benzenepropanenitrile 
• 133534-41-5 Phenoxy-phenyl-acetaldehyde 
• 107449-33-2 Phenoxy-phenyl-acetyl chloride 

Relevant articles and documents

Access to Optically Enriched α-Aryloxycarboxylic Esters via Carbene-Catalyzed Dynamic Kinetic Resolution and Transesterification

Optically active α-aryloxycarboxylic acids and their derivatives are important functional molecules. Disclosed here is a carbene-catalyzed dynamic kinetic resolution and transesterification reaction for access to this class of molecules with up to 99% yields and 99:1 er values. Addition of a chiral carbene catalyst to the ester substrate leads to two diastereomeric azolium ester intermediates that can quickly epimerize to each other and thus allows for effective dynamic kinetic resolution to be realized. The optically enriched ester products from our reaction can be quickly transformed to chiral herbicides and other bioactive molecules.

Highly Enantioselective Hydrogenation of Amides via Dynamic Kinetic Resolution Under Low Pressure and Room Temperature

High-throughput screening and lab-scale optimization were combined to develop the catalytic system trans-RuCl2((S,S)-skewphos)((R,R)-dpen), 2-PrONa, and 2-PrOH. This system hydrogenates functionalized α-phenoxy and related amides at room temperature under 4 atm H2 pressure to give chiral alcohols with up to 99% yield and in greater than 99% enantiomeric excess via dynamic kinetic resolution.