31397-22-5 Usage
General Description
The chemical "(2E)-2-[(1-methyl-1H-pyrrol-2-yl)methylidene]-N-phenylhydrazinecarbothioamide" is a hydrazine derivative with the molecular formula C12H12N4S. It contains a pyrrole ring and a phenyl group, as well as a carbonyl sulfur and a hydrazine functional group. (2E)-2-[(1-methyl-1H-pyrrol-2-yl)methylidene]-N-phenylhydrazinecarbothioamide may have potential biological activity as it contains an aromatic ring and a reactive sulfur atom, which could potentially interact with biological targets. The compound's chemical structure suggests it may have potential as a ligand or as a substrate for enzymatic reactions, and may be of interest for further investigation in medicinal chemistry.
Check Digit Verification of cas no
The CAS Registry Mumber 31397-22-5 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 3,1,3,9 and 7 respectively; the second part has 2 digits, 2 and 2 respectively.
Calculate Digit Verification of CAS Registry Number 31397-22:
(7*3)+(6*1)+(5*3)+(4*9)+(3*7)+(2*2)+(1*2)=105
105 % 10 = 5
So 31397-22-5 is a valid CAS Registry Number.
31397-22-5Relevant articles and documents
Novel Structural Hybrids of Pyrrole and Thiazole Moieties: Synthesis and Evaluation of Antibacterial and Antifungal Activities
Abbas, Samir Y.,Ali, Tarik E.,Assiri, Mohammed A.,El-Sharief, Marwa A. M. Sh,Gouda, Moustafa A.,Helal, Mohamed H.,Salem, Mohamed A.
, p. 990 - 996 (2021/12/29)
One of the best ways to design new biocidal agents is synthesizing hybrid molecules by combining two or more bioactive moieties in a single molecular scaffold. So, new series of pyrroles bearing a thiazole moiety were synthesized using 1-methyl-1H-pyrrole-2-carbaldehyde thiosemicarbazones 1a–c. Cyclization of thiosemicarbazone derivatives 1a–c with ethyl chloroacetate, ethyl 2-chloropropanoate, chloroacetone and phenacyl bromide afforded the corresponding thiazolidin-4-ones 2a–c, 5-methylthiazolidin-4-ones 3a–c, 4-methyl-2,3-dihydrothiazoles 4a–c, and 4-phenyl-2,3-dihydrothi-azoles 5a–c, respectively. The antimicrobial activity of the new thiazole derivatives was evaluated.
