31448-67-6

Basic information

• Product Name: dimethyl 2,4-dibromopentanedioate
• CAS NO: 31448-67-6
• Molecular Weight: 317.962
• Mol File: 31448-67-6.mol
• Article Data: 7

Chemical Properties

• CAS DataBase Reference: dimethyl 2,4-dibromopentanedioate(CAS DataBase Reference)
• NIST Chemistry Reference: dimethyl 2,4-dibromopentanedioate(31448-67-6)
• EPA Substance Registry System: dimethyl 2,4-dibromopentanedioate(31448-67-6)

Safety Data

• Hazardous Substances Data: 31448-67-6(Hazardous Substances Data)

Upstream product

• 67-56-1 methanol 
• 110-94-1 1,5-pentanedioic acid 
• 2873-74-7 gloutaric dichloride 
• 186581-53-3 diazomethane 
• 3479-80-9 α,α'-dibromoglutaric acid 
• 124-41-4 sodium methylate 
• 3425-64-7 d,l-α,α'-dibromoglutaric acid 

Downstream Products

• 826-34-6 dimethyl cis-cyclopropane-1,2-dicarboxylate 
• 826-35-7 dimethyl trans-1,2-cyclopropanedicarboxylate 
• 928853-01-4 2-(5-benzyl-tetrazol-2-yl)-4-bromo-pentanedioic acid dimethyl ester 
• 869494-14-4 3-benzyl-3,6-diazabicyclo[3.1.1]heptane 
• 869494-18-8 6-propionyl-3,6-diazabicyclo[3.1.1]heptane 
• 869494-16-6 3,6-diazabicyclo[3.1.1]heptane-6-carboxylic acid tert-butyl ester 
• 21055-50-5 dimethyl 2,7-diisothiocyanatosuberate 
• 1393565-46-2 cis-1,2-diisothiocyanatocyclohexane-1,2-dicarboxylate 
• 127310-50-3 cis-azetidine-2,4-dicarboxylic acid dimethyl ester 
• 121050-11-1 cis-1-benzylazetidine-2,4-dicarboxylic acid diamide 

Relevant articles and documents

Synthesis and Bioactivity of a New Class of Rigid Glutamate Analogues. Modulators of the N-Methyl-D-aspartate Receptor

A variety of derivatives of azetidine-2,4-dicarboxylic acid were synthesized and examined for their ability to stimulate 45Ca2+ uptake in cultures of cerebellar granule cells.Of the compounds tested, the cis-azetidine-2,4-dicarboxylic acid (10f

Enolates of 2-isothiocyanatocarboxylic esters: Synthesis of thiazolo[5,4-d]-thiazole derivatives and 2-thioxo-1,3-thiazolidine-4- carboxylates

An oxidative dimerization of titanium(IV) enolates derived from menthyl esters of 2-isothiocarboxylic acids leads to radical coupling followed by cyclization. This cascade reaction gives thiazolo[5,4-d]thiazole derivatives as pure enantiomers. Under simil

Stereoselective 1,3-debromination reactions

The metallate, PPN(1+)Cr(CO)4NO(1-), was used for the 1,3-debrominative reductive cyclization of the (+/-) and meso isomers of dimethyl 2,4-dibromoglutarate and dimethyl 2,4-dibromo-2,4-dimethylglutarate.In both (+/-) isomers, the reaction is stereospecific in giving the trans cyclopropane product.In the meso case, the reaction is unselective in the first case, but distinctly favors the cis cyclopropane isomer in the second set of compounds.This (+/-) and meso pair thus represent the first example of near stereospecifity in the debromination of both 1,3-dibromo diasteromers.Using an enantiomerically enriched dimethyl 2,4-dibromo glutarate, and determining the absolute stereochemistry of the cyclopropane product, it was found that a strict double inversion () mechanism is involved in the (+/-) debromination reaction and presumably also in the near-stereospecific meso case reported above.