3149-25-5

Basic information

• Product Name: 1,3-Dimethyl-2-quinoxalinone
• Synonyms: 1,3-Dimethyl-2-quinoxalinone;1,3-dimethylquinoxalin-2-one;1,3-DiMethyl-1H-quinoxalin-2-one
• CAS NO: 3149-25-5
• Molecular Formula: C₁₀H₁₀N₂O
• Molecular Weight: 174.1992
• Mol File: 3149-25-5.mol
• Article Data: 1

Chemical Properties

• Melting Point: 86-87 °C
• Boiling Point: 303 °C at 760 mmHg
• Flash Point: 137 °C
• Appearance: /
• Density: 1.18 g/cm³
• Vapor Pressure: 0.000957mmHg at 25°C
• Refractive Index: 1.608
• PKA: 0.21±0.70(Predicted)
• CAS DataBase Reference: 1,3-Dimethyl-2-quinoxalinone(CAS DataBase Reference)
• NIST Chemistry Reference: 1,3-Dimethyl-2-quinoxalinone(3149-25-5)
• EPA Substance Registry System: 1,3-Dimethyl-2-quinoxalinone(3149-25-5)

Safety Data

• Hazardous Substances Data: 3149-25-5(Hazardous Substances Data)

Usage

Synthesis Reference(s)

Journal of Medicinal Chemistry, 44, p. 594, 2001 DOI: 10.1021/jm000282d

InChI:InChI=1/C10H10N2O/c1-7-10(13)12(2)9-6-4-3-5-8(9)11-7/h3-6H,1-2H3

Upstream product

• 1029963-81-2 2-azido-N-(2-iodophenyl)-N-methylpropanamide 

Downstream Products

• 67074-64-0 1,3-dimethyl-3,4-dihydroquinoxalin-2(1H)-one 
• 1501-41-3 3-bromomethyl-1H-1-methylquinoxalin-2-one 
• 14152-61-5 1-Methyl-2-oxo-dihydrochinoxalyl-(3)-brenztraubensaeure 
• 133528-78-6 1-Methyl-3-(1-phenyl-1H-pyrazol-4-yl)-1H-quinoxalin-2-one 
• 84561-61-5 [2-(4-Methyl-3-oxo-3,4-dihydro-quinoxalin-2-yl)-1-(4-nitro-phenyl)-ethylsulfanyl]-acetic acid 
• 84546-98-5 1-methyl-3-<2-(p-methoxyphenyl)-2-(o-aminophenylthio)ethyl>-2(1H)-quinoxalinone 
• 84546-96-3 1-methyl-3-<2-(p-nitrophenyl)-2-(phenylthio)ethyl>-2(1H)-quinoxalinone 
• 84546-97-4 1-methyl-3-<2-(p-methoxyphenyl)-2-(p-methylphenylthio)ethyl>-2(1H)-quinoxalinone 
• 84546-95-2 1-methyl-3-<2-(p-methoxyphenyl)-2-(phenylthio)ethyl>-2(1H)-quinoxalinone 
• 84547-01-3 [1-(4-Methoxy-phenyl)-2-(4-methyl-3-oxo-3,4-dihydro-quinoxalin-2-yl)-ethylsulfanyl]-acetic acid 
• 84547-00-2 [2-(4-Methyl-3-oxo-3,4-dihydro-quinoxalin-2-yl)-1-p-tolyl-ethylsulfanyl]-acetic acid 
• 84546-99-6 [2-(4-Methyl-3-oxo-3,4-dihydro-quinoxalin-2-yl)-1-phenyl-ethylsulfanyl]-acetic acid 
• 84546-94-1 1-methyl-3-<2-phenyl-2-(phenylthio)ethyl>-2(1H)-quinoxalinone 
• 93584-92-0 3-[(E)-2-(4-Dimethylamino-phenyl)-vinyl]-1-methyl-1H-quinoxaline-2-thione 

Relevant articles and documents

Iminyl radicals from α-azido o-iodoanilides via 1,5-H transfer reactions of aryl radicals: New transformation of α-azido acids to decarboxylated nitriles

(Chemical Equation Presented) The radical reaction of tributyltin hydride with o-iodo-N-methylanilides derived from α-azido acids provides an excellent access to α-(aminocarbonyl)iminyl radicals through 1,5-hydrogen transfer reaction of initially formed aryl radicals followed by β-elimination of dinitrogen from ensuing α-azido-α- (aminocarbonyl)alkyl radicals. The outcoming iminyls display a peculiar tendency to form corresponding nitriles by β-elimination of aminocarbonyl radicals.