315180-14-4 Usage
Description
Pyridine, 3-(chloromethyl)-2-fluoro(9CI) is a chemical compound with the molecular formula C6H5ClFN. It is a derivative of pyridine with a chlorine atom and a fluorine atom attached to the second and third carbon atoms of the ring. Pyridine, 3-(chloromethyl)-2-fluoro(9CI) is known for its high reactivity and is commonly used as a building block in the synthesis of pharmaceuticals, agrochemicals, and other organic compounds. Additionally, it finds applications in the production of specialty chemicals and as a reagent in organic chemistry reactions. Due to its potential to cause skin and eye irritation, as well as harmful effects if ingested or inhaled, Pyridine, 3-(chloromethyl)-2-fluoro(9CI) should be handled with caution.
Uses
Used in Pharmaceutical Industry:
Pyridine, 3-(chloromethyl)-2-fluoro(9CI) is used as a building block for the synthesis of various pharmaceuticals. Its unique structure allows for the development of new drugs with specific therapeutic properties.
Used in Agrochemical Industry:
In the agrochemical industry, Pyridine, 3-(chloromethyl)-2-fluoro(9CI) is utilized as a key intermediate in the production of agrochemicals, contributing to the development of effective pesticides and other agricultural products.
Used in Specialty Chemicals Production:
Pyridine, 3-(chloromethyl)-2-fluoro(9CI) is employed in the production of specialty chemicals, where its reactivity and unique structure enable the creation of high-value compounds for various applications.
Used as a Reagent in Organic Chemistry Reactions:
Pyridine, 3-(chloromethyl)-2-fluoro(9CI) serves as a valuable reagent in organic chemistry, facilitating a range of reactions and contributing to the advancement of chemical research and development.
Check Digit Verification of cas no
The CAS Registry Mumber 315180-14-4 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 3,1,5,1,8 and 0 respectively; the second part has 2 digits, 1 and 4 respectively.
Calculate Digit Verification of CAS Registry Number 315180-14:
(8*3)+(7*1)+(6*5)+(5*1)+(4*8)+(3*0)+(2*1)+(1*4)=104
104 % 10 = 4
So 315180-14-4 is a valid CAS Registry Number.
InChI:InChI=1/C6H5ClFN/c7-4-5-1-2-9-6(8)3-5/h1-3H,4H2
315180-14-4Relevant articles and documents
Substituted pyrazolopyridine derivatives and medicinal use thereof
-
, (2018/05/07)
The invention relates to substituted pyrazolopyridine derivatives represented by formula (I), and pharmaceutically acceptable salts, isomers, prodrugs and medicinal compositions thereof. Above compounds are stimulants of soluble guanylate cyclase. In the formula (I), R1 represents a thienyl group or a substituted pyridyl group, R2 represents -NH2, -NHCH3 or -NHC(=O)CH(CH3)2, R3 represents hydrogenor a C1-C4 alkyl group, and R4 represents a C1-C6 alkyl group. The invention also discloses a preparation method of the compounds and an application of the compounds as medicines, especially an application as cardiovascular disease treatment medicines, such as anti-pulmonary arterial hypertension medicines.
Modular Route to Azaindanes
Huang, Qi,Zard, Samir Z.
, p. 3895 - 3898 (2017/07/26)
A convergent radical based route to azaindanes is described, relying on the degenerative addition transfer of various substituted S-(pyridylmethyl)-O-ethyl dithiocarbonates (xanthates) to functional alkenes followed by radical cyclization onto the pyridine ring activated by protonation with trifluoroacetic acid. In one case, a richly decorated cyclohepta[b]pyridine could be assembled swiftly by allowing the first adduct to N-phenylmaleimide to undergo addition to N-allylphthalimide prior to cyclization.
Efficient pyridinylmethyl functionalization: Synthesis of 10,10-bis[(2-fluoro-4-pyridinyl)methyl]-9(10H)-anthracenone (DMP 543), an acetylcholine release enhancing agent
Pesti,Huhn,Yin,Xing,Fortunak,Earl
, p. 7718 - 7722 (2007/10/03)
2-Fluoro-4-methylpyridine (3) is efficiently functionalized by chlorination, hydrolysis and methane-sulfonylation into the novel alkylating agent 7. This mesylate is used for the bisalkylation of anthrone under carefully defined conditions to prepare the cognition enhancer drug candidate 1. This process proceeds in up to 37% overall yield and is adaptable for large scale synthesis.