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3154-99-2

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3154-99-2 Usage

General Description

2-cyclopropylbenzonitrile, also known as Cyclopropylbenzonitrile or CCBN, is a chemical compound with the molecular formula C10H8N. It is a colorless to pale yellow liquid that is used as a building block in the synthesis of pharmaceuticals and agrochemicals. 2-cyclopropylbenzonitrile is a useful intermediate for the production of various chemical products, including dyes, pigments, and insecticides. It is also used as a reagent in organic synthesis and pharmaceutical research. The compound is known for its unique chemical structure and versatile reactivity, making it a valuable component in the fine chemical industry. Despite its potential uses, caution should be exercised in handling 2-cyclopropylbenzonitrile due to its potential hazards as a toxic and irritant substance.

Check Digit Verification of cas no

The CAS Registry Mumber 3154-99-2 includes 7 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 4 digits, 3,1,5 and 4 respectively; the second part has 2 digits, 9 and 9 respectively.
Calculate Digit Verification of CAS Registry Number 3154-99:
(6*3)+(5*1)+(4*5)+(3*4)+(2*9)+(1*9)=82
82 % 10 = 2
So 3154-99-2 is a valid CAS Registry Number.

3154-99-2Relevant articles and documents

Facile synthesis of aryl(het)cyclopropane catalyzed by palladacycle

Zhang, Min,Cui, Xiuling,Chen, Xiaopei,Wang, Lianhui,Li, Jingya,Wu, Yusheng,Hou, Lifen,Wu, Yangjie

experimental part, p. 900 - 905 (2012/02/01)

Sphos (2-dicyclohexylphosphino-2′,6′-dimethoxy-1,1′- biphenyl) adduct of cyclopalladated ferrocenylimine (IIe) exhibited highly catalytic activity for the Suzuki cross-coupling reaction of cyclopropylboronic acid with aryl(het) halides with 1 mol % catalyst loading. This process was applied to both of aryl and heteroaryl halides (Br and Cl), and made the various arylcyclopropane and heteroarylcyclopropane to be easily synthesized. A variety of substituents on the aryl halides, such as alkyl, acetyl, benzoyl, ether, formyl, carboxylate, methoxy, nitro and cyano were tolerated.

General and user-friendly protocol for the synthesis of functionalized aryl- and heteroaryl-cyclopropanes by Negishi cross-coupling reactions

Coleridge, Brian M.,Bello, Charles S.,Leitner, Andreas

experimental part, p. 4475 - 4477 (2009/12/03)

The introduction of an unsubstituted cyclopropyl moiety was efficiently accomplished via Negishi cross-coupling of cyclopropylzinc bromide with functionalized aryl halides in high yields and fast reaction rates. The stability and the efficient one-step sy

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