31638-66-1Relevant articles and documents
Electrochemical synthesis of copper(i) acetylides: Via simultaneous copper ion and catalytic base electrogeneration for use in click chemistry
Seavill, Peter W.,Holt, Katherine B.,Wilden, Jonathan D.
, p. 29300 - 29304 (2019/09/30)
We report an efficient and sustainable electrochemical synthesis of copper(i) acetylides using simultaneous copper oxidation and Hofmann elimination of quaternary ammonium salts. The electrochemically-generated base was also regenerated electrochemically,
Photochemical Hexadehydro-Diels-Alder Reaction
Xu, Feng,Xiao, Xiao,Hoye, Thomas R.
supporting information, p. 8400 - 8403 (2017/07/06)
We demonstrate that the hexadehydro-Diels-Alder (HDDA) cycloisomerization reaction to produce reactive benzyne derivatives can be initiated photochemically. As with the thermal variant of the HDDA process, the reactive intermediates are formed in the absence of reagents or the resulting byproducts required for the generation of benzynes by traditional methods. This photo-HDDA (or hν-HDDA) reaction occurs at much lower temperatures (including even at -70 °C) than the thermal HDDA, but the benzynes produced behave in the same fashion with respect to their trapping reactions, suggesting they are of the same electronic state.
Cu-catalyzed ring opening reaction of 2H-azirines with terminal alkynes: An easy access to 3-alkynylated pyrroles
Li, Tengfei,Xin, Xiaoyi,Wang, Chunxiang,Wang, Dongping,Wu, Fan,Li, Xincheng,Wan, Boshun
, p. 4806 - 4809 (2015/04/27)
A highly efficient Cu-catalyzed ring expansion reaction of 2H-azirines with terminal alkynes has been developed. This transformation provides a powerful method for the synthesis of 3-alkynyl polysubstituted pyrroles under mild conditions in good yields. The direct transformation process, specific selectivity, and good tolerance to a variety of substituents make it an alternative approach to the reported protocols.