32046-43-8 Usage
Description
5-Iodopyridine-2-carboxylic acid is an organic compound with the molecular formula C6H4INO2. It is a derivative of pyridine-2-carboxylic acid, featuring an iodine atom at the 5th position. 5-Iodopyridine-2-carboxylic acid has potential applications in various fields due to its unique chemical properties.
Uses
Used in Pharmaceutical Industry:
5-Iodopyridine-2-carboxylic acid is used as a key intermediate in the synthesis of various pharmaceutical compounds. Its unique structure allows it to be a valuable building block for the development of new drugs with specific therapeutic properties.
Used in Anticancer Applications:
5-Iodopyridine-2-carboxylic acid is used as a precursor for the preparation of bis(5-iodopicolinato)oxovanadium(IV), which is an antidiabetic agent. 5-Iodopyridine-2-carboxylic acid has shown potential in managing blood sugar levels and improving the treatment of diabetes.
Used in Insulinomimetic Activity:
The zinc(II) complex with 5-Iodopyridine-2-carboxylic acid has demonstrated insulinomimetic activity, which means it can mimic the effects of insulin in the body. This property makes it a promising candidate for the development of new treatments for diabetes and related metabolic disorders.
Check Digit Verification of cas no
The CAS Registry Mumber 32046-43-8 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 3,2,0,4 and 6 respectively; the second part has 2 digits, 4 and 3 respectively.
Calculate Digit Verification of CAS Registry Number 32046-43:
(7*3)+(6*2)+(5*0)+(4*4)+(3*6)+(2*4)+(1*3)=78
78 % 10 = 8
So 32046-43-8 is a valid CAS Registry Number.
InChI:InChI=1/C6H4INO2/c7-4-1-2-5(6(9)10)8-3-4/h1-3H,(H,9,10)
32046-43-8Relevant articles and documents
DERIVATIVES OF 6,7-DIHYDRO-5H-IMIDAZO[1,2-α]IMIDAZOLE-3- CARBOXYLIC ACID AMIDES
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Page/Page column 112-113, (2009/07/03)
Derivatives of 6,7-dihydro-5H-imidazo[1,2-α]imidazole-3-carboxylic acid amide exhibit good inhibitory effect upon the interaction of CAMs and Leukointegrins and are thus useful in the treatment of inflammatory disease.
The preparation of Some 4- and 5-Substituted Pyridine-2-carboxylic Acids as Fusaric Acid Analogues.
Oehlke, J.,Schroetter, E.,Dove, S.,Schick, H.,Niedrich, H.
, p. 591 - 596 (2007/10/02)
In view of future studies on the structure-activity relationships involved in the inhibition of dopamine β-hydroxylase, the authors synthetized 5-substituted picolinic acids and 4-substituted fusaric acids selected by means of a random sampling procedure suited for small series.On this occasion, they succeeded in improving markedly the well-known synthesis of 5-nitropicolinic acid via a Rosenmund-v.Braun reaction with 2-bromo-5-nitropyridine. 5-Hydroxypicolinic acid which is easily accessible in the same way could be converted into 5-alkyloxypicolinic acids by reaction with alkyl halides in DMSO in the presence of silver oxide. 4-Substituted fusaric acids became accessible via 5-n-butyl-2-methyl-4-nitropyridine-N-oxide.
