321535-19-7

Basic information

• Product Name: 6-methoxy-[2,3']bipyridinyl-5'-carboxylic acid methyl ester
• Synonyms: 6-methoxy-[2,3']bipyridinyl-5'-carboxylic acid methyl ester
• CAS NO: 321535-19-7
• Molecular Weight: 244.25
• Mol File: 321535-19-7.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: 6-methoxy-[2,3']bipyridinyl-5'-carboxylic acid methyl ester(CAS DataBase Reference)
• NIST Chemistry Reference: 6-methoxy-[2,3']bipyridinyl-5'-carboxylic acid methyl ester(321535-19-7)
• EPA Substance Registry System: 6-methoxy-[2,3']bipyridinyl-5'-carboxylic acid methyl ester(321535-19-7)

Safety Data

• Hazardous Substances Data: 321535-19-7(Hazardous Substances Data)

Upstream product

• 29681-44-5 5-bromo-3-pyridine carboxylic acid methyl ester 
• 40473-07-2 6-bromo-2-methoxypyridine 

Downstream Products

• 78867-61-5 3-benzyl-1,2,3,4,5,6-hexahydro-1,5-methano-pyrido[1,2-a][1,5]diazocin-8-one 
• 321535-22-2 1'-benzyl-6-methoxy-1',4'-dihydro-[2,3']bipyridinyl-5'-carboxylic acid methyl ester 
• 485-35-8 1,2,3,4,5,6-hexahydro-1,5-methano-pyrido[1,2-a][1,5]diazocin-8-one 

Relevant articles and documents

Total synthesis of (±)-cytisine

(equation presented) The nicotine partial agonist cytisine was prepared in five steps featuring an "in situ" Stille or Suzuki biaryl pyridine coupling. Differentiation of the pyridyl rings was accomplished via selective benzylation and then reduction of a pyridinium ring. The penultimate diazabicyclo[3.3.1]-nonane intermediate was obtained with high diastereoselectivity. A similar sequence has been employed for the synthesis of novel derivative 9-methoxycytisine.