32230-29-8

Basic information

• Product Name: C₁₀H₁₃NO₃
• Synonyms: C₁₀H₁₃NO₃
• CAS NO: 32230-29-8
• Molecular Weight: 195.218
• Mol File: 32230-29-8.mol
• Article Data: 2

Chemical Properties

• CAS DataBase Reference: C₁₀H₁₃NO₃(CAS DataBase Reference)
• NIST Chemistry Reference: C₁₀H₁₃NO₃(32230-29-8)
• EPA Substance Registry System: C₁₀H₁₃NO₃(32230-29-8)

Safety Data

• Hazardous Substances Data: 32230-29-8(Hazardous Substances Data)

Upstream product

• 4925-88-6 2,5-dimethoxy-4-methylbenzaldehyde 

Downstream Products

• 1391056-94-2 C₁₆H₉Cl₂NO₃ 
• 1391056-92-0 C₁₈H₁₅Cl₂NO₃ 
• 1391056-76-0 C₁₆H₁₁NO₃ 
• 1391056-75-9 C₁₈H₁₇NO₃ 
• 1391056-87-3 C₂₂H₁₅NO₄ 
• 1391056-80-6 C₂₄H₂₁NO₄ 
• 1391056-88-4 C₁₇H₁₀F₃NO₃ 
• 1391056-81-7 C₁₉H₁₆F₃NO₃ 
• 1391056-84-0 C₁₆H₁₀ClNO₃ 
• 1391056-77-1 C₁₈H₁₆ClNO₃ 
• 1391056-90-8 C₁₅H₁₅NO₃ 
• 1391056-83-9 C₁₇H₂₁NO₃ 
• 1391056-93-1 C₁₃H₁₃NO₃ 
• 1391056-91-9 C₁₅H₁₉NO₃ 

Relevant articles and documents

Synthesis of Novel Diaziridinyl Quinone Isoxazole Hybrids and Evaluation of Their Anti-Cancer Activity as Potential Tubulin-Targeting Agents

Two series of diaziridinyl quinone isoxazole derivatives were prepared and evaluated for their cytotoxic activity against MCF7, HeLa, BT549, A549 and HEK293 cell lines and interaction with tubulin. Compounds (6a-m) showed promising activity against all the 5 human cancer cell lines. Compounds 6a, 6e and 6 m were potent [IC 50 ranging between 2.21 μg to 2.87 μg] on ER-positive MCF7 cell line similar to the commercially available drug molecule Doxorubicin. The results from docking models are in consistent with the experimental values which demonstrated the favourable binding modes of compounds 6a-m to the interface of α- and β-tubulin dimer.