3254-79-3Relevant articles and documents
Microwave-assisted one-step synthesis of fenamic acid hydrazides from the corresponding acids
Aboul-Fadl, Tarek,Abdel-Aziz, Hatem A.,Kadi, Adnan,Bari, Ahmed,Ahmad, Pervez,Al-Samani, Tilal,Ng, Seik Weng
experimental part, p. 3544 - 3551 (2011/06/25)
A facile and efficient method for synthesis of fenamic acid hydrazides from their acids in one-step reaction under microwave irradiation and solvent-free conditions was developed. Compared with the two-step conventional heating method, the process was simple, the reaction time was very short and the yields were almost quantitative.
FENAMATE 1,3,4-THIADIAZOLES AND 1,3,4-OXADIAZOLES AS ANTIINFLAMMATORY AGENTS
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, (2008/06/13)
The present invention is novel compounds which are 1,3,4-thiadiazoles and 1,3,4-oxadiazoles, and pharamaceutically acceptable acid addition or base salts thereof having activity as inhibitors of singly or together 5-lipoxygenase and cyclooxygenase, and pharmaceutical compositions or methods of use therefor.
TRIAZOLE DERIVATIVES OF FENAMATES AS ANTIINFLAMMATORY AGENTS
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, (2008/06/13)
The present invention is novel compounds which are 1,2,4-triazoles, derivatives of fenamates and pharmaceutically acceptable additions and base salts thereof, pharmaceutical compositions and methods of use thereof. The invention compounds are now found to have activity as inhibitors of 5-lipoxygenase and/or cyclooxygenase providing treatment of conditions advantageously affected by such inhibition including inflammation, arthritis, pain, fever, and the like