3274-19-9

Basic information

• Product Name: N-anthraquinon-1-ylacetamide
• Synonyms: N-Anthraquinon-1-ylacetamide; AI3-17606; Acetamide, N-(9,10-dihydro-9,10-dioxo-1-anthracenyl)-; N-(9,10-dioxo-9,10-dihydroanthracen-1-yl)acetamide
• CAS NO: 3274-19-9
• Molecular Formula: C₁₆H₁₁NO₃
• Molecular Weight: 265.2634
• EINECS: 221-901-7
• Mol File: 3274-19-9.mol
• Article Data: 8

Chemical Properties

• Boiling Point: 541.8°C at 760 mmHg
• Flash Point: 225.2°C
• Density: 1.38g/cm³
• Vapor Pressure: 8.37E-12mmHg at 25°C
• Refractive Index: 1.683
• CAS DataBase Reference: N-anthraquinon-1-ylacetamide(CAS DataBase Reference)
• NIST Chemistry Reference: N-anthraquinon-1-ylacetamide(3274-19-9)
• EPA Substance Registry System: N-anthraquinon-1-ylacetamide(3274-19-9)

Safety Data

• Hazardous Substances Data: 3274-19-9(Hazardous Substances Data)

Usage

General Description

N-anthraquinon-1-ylacetamide is a chemical compound with a molecular structure consisting of an anthraquinone group attached to an acetamide group. It is a derivative of anthraquinone and has potential applications in medicinal and pharmaceutical fields due to its reported biological activities. Anthraquinone derivatives have been studied for their antibacterial, antifungal, anti-inflammatory, and antitumor properties, and N-anthraquinon-1-ylacetamide may possess similar characteristics. Further research and testing are necessary to fully understand the potential uses and effects of this compound. Additionally, it is important to consider potential risks and hazards associated with the handling and use of N-anthraquinon-1-ylacetamide due to its chemical nature.

Upstream product

• 60840-08-6 2-acetylamino-2'-carboxy-diphenylmethane 
• 610-49-1 1-aminoanthracene 
• 63512-12-9 N-(anthracen-1-yl)acetamide 
• 64-19-7 acetic acid 
• 10165-25-0 1-acetylamino-4-chloro-anthraquinone 
• 82-45-1 1-amino-9,10-anthracenedione 
• 75-36-5 acetyl chloride 
• 60-35-5 acetamide 
• 108-24-7 acetic anhydride 
• 127-09-3 sodium acetate 

Downstream Products

• 82-38-2 1-(methylamino)anthraquinone 
• 82-45-1 1-amino-9,10-anthracenedione 
• 22281-18-1 naphtho[1',2',3':4,5]quino[2,1-b]quinazoline-5,10-dione 
• 2872-47-1 1-amino-4-chloroanthraquinone 
• 6937-74-2 1-amino-4-nitroanthraquinone 

Relevant articles and documents

Microbial metabolism of 1-aminoanthracene by Beauveria bassiana

The carcinogen and mutagen, 1-aminoanthracene, was efficiently metabolized by the fungal strain Beauveria bassiana ATCC 7159 to yield three new metabolites identified as 1-acetamido-5-[(4′-O-methyl-β-d-glucopyranosyl)oxy]anthracene, 1-acetamido-8-[(4′-O-methyl-β-d-glucopyranosyl)oxy]anthraquinone, and 1-acetamido-6-[(4′-O-methyl-β-d-glucopyranosyl)oxy]anthraquinone, together with 1-acetamidoanthracene and 1-acetamidoanthraquinone. Formation of these metabolites suggests that the metabolic pathways of 1-aminoanthracene in B. bassiana ATCC 7159 involve acetylation, oxidation, hydroxylation, and O-methylglucosylation.

Silica-supported boric acid catalyzed synthesis of dihydropyrimidin-2-ones, bis(indolyl)methanes, esters and amides

Silica-supported boric acid (H3BO3-SiO2) has been established as a green, efficient and recyclable catalyst for the synthesis of dihydropyrimidin-2-ones, bis(indolyl)methanes, and acetylation of alcohols, phenols, amines and thiols under solvent free conditions. The main features of the present method include clean reaction, mild conditions, low loading of environment friendly catalyst and easy workup procedure. The catalyst can be recycled at least five times without any significant loss in activity.

SOME RELATIONSHIPS IN THE SYNTHESIS OF BIARYLS FROM HALOGENOANTHRAQUINONES

The effects of the solvent and the concentration of the reagents on the reaction path and on the results of the synthesis of biaryls from halogenoanthraquinones were investigated for the case of the reaction of 1-chloro-4-benzoylaminoanthraquinone with copper.The use of concentrated reaction mixtures and of donating aprotic dipolar solvents with copper-aryl halide ratios slightly exceeding an equimolar ratio leads to a reduction in the induction period and to an increase in the yield of the biaryls.This explained by interaction between the copmonents of the metal-aryl halide-solvent complex.