63512-12-9

Basic information

• Product Name: Acetamide, N-1-anthracenyl-
• Synonyms: Acetamide, N-1-anthracenyl-
• CAS NO: 63512-12-9
• Molecular Formula: C₁₆H₁₃NO
• Molecular Weight: 235.2805
• Mol File: 63512-12-9.mol
• Article Data: 4

Chemical Properties

• Boiling Point: 506.9°Cat760mmHg
• Flash Point: 302.8°C
• Appearance: /
• Density: 1.233g/cm³
• Vapor Pressure: 2.12E-10mmHg at 25°C
• Refractive Index: 1.73
• CAS DataBase Reference: Acetamide, N-1-anthracenyl-(CAS DataBase Reference)
• NIST Chemistry Reference: Acetamide, N-1-anthracenyl-(63512-12-9)
• EPA Substance Registry System: Acetamide, N-1-anthracenyl-(63512-12-9)

Safety Data

• Hazardous Substances Data: 63512-12-9(Hazardous Substances Data)

Usage

InChI:InChI=1/C16H13NO/c1-11(18)17-16-8-4-7-14-9-12-5-2-3-6-13(12)10-15(14)16/h2-10H,1H3,(H,17,18)

Upstream product

• 195045-31-9 9,10-dihydro-[1]anthrylamine 
• 610-49-1 1-aminoanthracene 
• 64-19-7 acetic acid 
• 108-24-7 acetic anhydride 
• 75-36-5 acetyl chloride 
• 82-45-1 1-amino-9,10-anthracenedione 

Downstream Products

• 13936-76-0 N-(anthracen-1-yl)-N-benzylacetamide 
• 3274-19-9 1-(acetylamino)anthraquinone 
• 84-56-0 1-Azabenzanthracene 
• 82-45-1 1-amino-9,10-anthracenedione 

Relevant articles and documents

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Polycyclic maleimide-based derivatives as first dual modulators of neuronal calcium channels and GSK-3β for Alzheimer's disease treatment

Current healthcare has significantly increased the average life expectancy, leading to a consequently greater incidence of age-related diseases, such as Alzheimer's disease. Following a multitarget approach, in this paper a series of polycyclic maleimide-based derivatives were designed and synthesized aimed at simultaneously modulate neuronal calcium channels and glycogen synthase kinase 3-beta (GSK-3β), validated targets to combat Alzheimer’ disease. Different structural modifications were performed on the polycyclic scaffold in order to investigate the structure-activity relationships and compound 10 emerged as a promising non-toxic lead compound, endowed with calcium modulating brain-addressed properties and significant GSK-3β inhibitory activity. Moreover, the easily affordable polycyclic core appears as a new appealing privileged structure in medicinal chemistry.

Photochemical and Electrochemical Oxidation Reactions of Surface-Bound Polycyclic Aromatic Hydrocarbons

The oxidation reactions of two PAH, i.e., pyrene and anthracene, attached covalently to silica, indium-doped tin oxide (ITO), and gold surfaces were studied. For both pyrene and anthracene, electrochemical and photochemical oxidation produced first a monohydroxy-PAH followed by the formation of dihydroxy/dione derivatives. Although the products of electrochemical or photochemical transformations were the same, the mechanism of each reaction might be different. In the case of electrochemical oxidation, no effect of oxygen dissolved in the solution on the voltammetric behavior was observed. The photodegradation of pyrene could occur through two paths, i.e., electron transfer and the reaction of pyrene with generated singlet oxygen. Singlet oxygen was not involved in the photochemical transformation of surface bound pyrene and the electron-transfer mechanism was dominant. The reaction of anthracene with water led to the formation of hydroxyanthracene and anthraquinones. The electron-transfer mechanism was dominant as the initial step of anthracene oxidation as well.