327617-63-0

Basic information

• Product Name: N-(2(R)-Methyl-2-tetrahydrofuroyl)-(L)-4-(2,6-dimethoxy-4-(1,2,4-triazol-1-yl-methyl)phenyl)phenylalanine
• CAS NO: 327617-63-0
• Molecular Weight: 494.547
• Mol File: 327617-63-0.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: N-(2(R)-Methyl-2-tetrahydrofuroyl)-(L)-4-(2,6-dimethoxy-4-(1,2,4-triazol-1-yl-methyl)phenyl)phenylalanine(CAS DataBase Reference)
• NIST Chemistry Reference: N-(2(R)-Methyl-2-tetrahydrofuroyl)-(L)-4-(2,6-dimethoxy-4-(1,2,4-triazol-1-yl-methyl)phenyl)phenylalanine(327617-63-0)
• EPA Substance Registry System: N-(2(R)-Methyl-2-tetrahydrofuroyl)-(L)-4-(2,6-dimethoxy-4-(1,2,4-triazol-1-yl-methyl)phenyl)phenylalanine(327617-63-0)

Safety Data

• Hazardous Substances Data: 327617-63-0(Hazardous Substances Data)

Upstream product

• 41253-21-8 sodium triazole 

Relevant articles and documents

Heterocycle amides as cell adhesion inhibitors

Compounds of Formula I are antagonists of VLA-4 and/or α4β7, and as such are useful in the inhibition or prevention of cell adhesion and cell-adhesion mediated pathologies. These compounds may be formulated into pharmaceutical compositions and are suitable for use in the treatment of AIDS-related dementia, allergic conjunctivitis, allergic rhinitis, Alzheimer's disease, asthma, atherosclerosis, autologous bone marrow transplantation, certain types of toxic and immune-based nephritis, contact dermal hypersensitivity, inflammatory bowel disease including ulcerative colitis and Crohn's disease, inflammatory lung diseases, inflammatory sequelae of viral infections, meningitis, multiple sclerosis, multiple myeloma, myocarditis, organ transplantation, psoriasis, pulmonary fibrosis, restenosis, retinitis, rheumatoid arthritis, septic arthritis, stroke, tumor metastasis, uveititis, and type I diabetes.