33000-65-6Relevant articles and documents
Facile Synthesis of 2-Alkoxy-2-aryloxiranes
Kimpe, Norbert De,Buyck, Laurent De,Verhe, Roland,Schamp, Niceas
, p. 3631 - 3636 (2007/10/02)
Tertiary α-bromoalkyl aryl ketones 1 were converted into 2-alkoxy-2-aryloxiranes 4 exclusively by reaction with excess potassium carbonate in the corresponding dry alcohol.Silver carbonate in a dry alcohol with these α-bromo ketones yielded competitively formation of 2-alkoxyoxiranes and semi-benzilic Favorskii rearrangement (-> 5), while silver hexafluoroantimonate in the same medium afforded the latter rearrangement reaction exclusively.