33105-93-0

Basic information

• Product Name: CarbaMicacid,N,N'-1,2-ethanediylbis-,C,C'-bis(1,1-diMethylethyl)ester
• Synonyms: CarbaMicacid,N,N'-1,2-ethanediylbis-,C,C'-bis(1,1-diMethylethyl)ester;N,N'-Bis(tert-butoxycarboxyl)-1,2-diaMinoethane;Di-tert-butyl ethane-1,2-diyldicarbaMate;N,N'-Bis(tert-butoxycarbonyl)-1,2-diaminoethane;tert-butyl ethane-1,2-diyldicarbamate;N,N'-diBoc-ethylenediamine
• CAS NO: 33105-93-0
• Molecular Formula: C₁₂H₂₄N₂O₄
• Molecular Weight: 260.32996
• Mol File: 33105-93-0.mol
• Article Data: 27

Chemical Properties

• Appearance: /
• Storage Temp.: Sealed in dry,Room Temperature
• CAS DataBase Reference: CarbaMicacid,N,N'-1,2-ethanediylbis-,C,C'-bis(1,1-diMethylethyl)ester(CAS DataBase Reference)
• NIST Chemistry Reference: CarbaMicacid,N,N'-1,2-ethanediylbis-,C,C'-bis(1,1-diMethylethyl)ester(33105-93-0)
• EPA Substance Registry System: CarbaMicacid,N,N'-1,2-ethanediylbis-,C,C'-bis(1,1-diMethylethyl)ester(33105-93-0)

Safety Data

• Hazardous Substances Data: 33105-93-0(Hazardous Substances Data)

Usage

General Description

CarbaMicacid, N,N'-1,2-ethanediylbis-, C,C'-bis(1,1-diMethylethyl)ester is a chemical compound that is also known as the bis(1,1-dimethylethyl) 1,2-ethanediyl ester of carbamic acid. It is a colorless liquid that is primarily used as a solvent and intermediate in the production of other chemicals. CarbaMicacid,N,N'-1,2-ethanediylbis-,C,C'-bis(1,1-diMethylethyl)ester is also known for its low toxicity and is commonly used in the pharmaceutical and agrochemical industries. Additionally, it is used in the production of polymers and as a plasticizer. It is important to handle this chemical with care and to follow proper safety protocols when working with it.

Upstream product

• 24424-99-5 di-tert-butyl dicarbonate 
• 107-15-3 ethylenediamine 
• 58632-95-4 2-(tert-Butoxycarbonyloxyimino)-2-phenylacetonitrile 
• 1070-19-5 N-(tert-butyloxycarbonyl) azide 

Downstream Products

• 1265900-61-5 C₂₀H₃₀N₂O₆S 
• 882645-09-2 1,4-Bis(tert-butoxycarbonyl)-1,4-diazepane 
• 459417-40-4 di-tert-butyl 6-oxo-1,4-diazepane-1,4-dicarboxylate 
• 79513-35-2 N-(tert-butyloxycarbonyl)-1,2-ethanediamine hydrochloride 

Relevant articles and documents

Search for the pharamcophore of the K+ channel blocker, apamin

The suggestion that the arginine residues, 13Arg and 14Arg, in the octadecapeptide apamin 1 are critically important to its action in blocking Ca2+-dependent K+ channels (and hence part of the 'pharmacophore') has been investigated by examining small peptides containing Arg-Arg or Lys-Arg. Bisguanidine derivatives modelled on the Arg-Arg partial pharmacophore have also been synthesised and tested; in particular, N-(2-guanidinoethyl)-3[N1-(2-guanidinoethyl)carbamoyl]-trans-propena mide 11 and its higher homologue 12. None of the compounds showed more than weak activity (K(i) > 10-5 M) indicating that although the Arg-Arg fragment may be necessary, it is not a sufficient atom grouping for the pharmacophore.

Synthesis and photoluminescence study of di-dendron dendrimers derived from mono-Boc-protected ethylenediamine cores

This work is focused on the synthesis and optical properties of cone-shaped structural feature di-dendron polyamidoamine dendrimers up to the third generation with mono-Boc-protected ethylenediamine (EDA) as a core. Strong UV absorbance spectra and fluorescence spectra from di-dendron dendrimers with different terminal groups (-NH2, -COOCH3) were studied under different conditions by varying experimental parameters such as concentration and pH. The optical density and fluorescence intensities increased when di-dendron dendrimers generation number increased from 0.5 to 3.0. It was confirmed that the concentration of di-dendron dendrimers plays an important role in fluorescence intensity. The increase in fluorescence intensity was linear in low concentration regions, but the intensity increased slowly in high concentration regions. The results also showed a rapid increase in fluorescence intensity at low pH. The formation of a fluorescence-emitting moiety had a close relationship to protonated tertiary amine groups in di-dendron dendrimers derived from mono-Boc-protected EDA cores. Furthermore, the formation of fluorescent chemical species was irreversible. Copyright

Formation of a tris(catecholato) iron(iii) complex with a nature-inspired cyclic peptoid ligand

Siderophore-mimicking macrocyclic peptoids were synthesized. Peptoid3with intramolecular hydrogen bonds showed an optimally arranged primary coordination sphere leading to a stable catecholate-iron complex. The tris(catecholato) structure of 3-Fe(iii) was determined with UV-vis, fluorescence, and EPR spectroscopies and DFT calculations. The iron binding affinity was comparable to that of deferoxamine, with enhanced stability upon air exposure.

A cardiovascular drug fasudil hydrochloride intermediate simple synthesis of process

The invention discloses a cardiovascular drug fasudil hydrochloride intermediate simple synthesis process, taking ethylenediamine, BOC anhydride, DCM into the reaction bottle stirring, GC to intermediate state the reaction is complete, the reaction solution is concentrated under reduced pressure, concentrate, tetrahydrofuran to stir until completely dissolved, addition of sodium methoxide, thermal insulation stirring [...] 1, 3 - dibromo propane, thermal insulation to stir until the reaction is complete, the reaction solution is poured into ice water, extracted with ethyl acetate twice, combined with the organic phase, a washed, dried with anhydrous sodium sulfate, concentrated under reduced pressure to dry, taking concentrated intermediate, 40% sodium hydroxide, ethanol into the reaction bottle stirring, the reaction solution is heated to reflux, thermal insulation reaction to intermediate state hydrolysis, reverse the ice water, for two armor uncle ether extraction, the combined organic phase, a washed, dried with anhydrous sodium sulfate, concentrated under reduced pressure to dry, adding hexane stirring crystallization, to obtain the product, yield 87.0%, GC99%, raw materials of this invention is simple and easy, the product has high purity, simple and convenient operation, the work efficiency is high.

CHEMICAL BLOWING AGENT AND THERMALLY EXPANDABLE THERMOPLASTIC COMPOSITION

The present invention relates to a chemical blowing agent comprising at least one tertiary alkyl carbamate. The chemical blowing agent can be activated thermally and is suitable for foaming thermoplastic materials and can for example be incorporated into thermally expandable baffle and/or reinforcement elements which are used in automotive manufacturing and building insulation.