33133-45-8

Basic information

• Product Name: Benzene, 1-bromo-4-(2-propynyloxy)-
• CAS NO: 33133-45-8
• Molecular Formula: C9H7BrO
• Molecular Weight: 211.058
• Mol File: 33133-45-8.mol
• Article Data: 39

Chemical Properties

• CAS DataBase Reference: Benzene, 1-bromo-4-(2-propynyloxy)-(CAS DataBase Reference)
• NIST Chemistry Reference: Benzene, 1-bromo-4-(2-propynyloxy)-(33133-45-8)
• EPA Substance Registry System: Benzene, 1-bromo-4-(2-propynyloxy)-(33133-45-8)

Safety Data

• Hazardous Substances Data: 33133-45-8(Hazardous Substances Data)

Upstream product

• 861374-56-3 (2-bromo-allyl)-(4-bromo-phenyl)-ether 
• 106-41-2 4-bromo-phenol 
• 107-19-7 propargyl alcohol 
• 13610-02-1 1-phenoxy-2-propyne 
• 106-96-7 propargyl bromide 
• 624-65-7 2-propynyl chloride 
• 108244-33-3 (4-bromo-phenyl)-(2,3-dibromo-propyl)-ether 

Downstream Products

• 18385-87-0 6-bromo-2H-benzopyran 
• 1196658-83-9 1-(3,4,6-tri-O-acetyl-1,5-anhydro-2-deoxy-D-galactitol-2-yl)-4-(4-bromophenoxy)methyl-1,2,3-triazole 
• 54965-04-7 5-bromo-2-methylbenzo[b]furan 

Relevant articles and documents

Acetylcholinesterase-induced fluorescence turn-off of an oligothiophene-grafted quartz surface sensitive to myristoylcholine

Conjugated polyelectrolytes (CPEs) have recently emerged as label-free materials for biosensing due to their intrinsic ability to transduce an amplified optical signal in response to interactions with different analytes. Herein, the conformational change of an anionic oligothiophene is exploited to generate a unique fluorescent response upon interaction with myristoylcholine (MyrCh). The variations observed in spectroscopic signals are explained in terms of a synergistic combination of hydrophobic and electrostatic forces involving the oligothiophene chains and MyrCh molecules, inducing the disassembling of oligothiophene chains. The enzyme acetylcholinesterase (AChE) is able to reverse this effect by catalyzing the hydrolysis of MyrCh; hence, its enzymatic activity can be monitored through the variation of fluorescence emission of the system. The oligothiophene sensing probe retains its conformational sensitivity with regard to the AChE-mediated cleavage of MyrCh upon immobilization onto a quartz substrate, which is accomplished by a "grafting onto" approach based on click chemistry. These results are encouraging for the further development of such a label-free system towards the fabrication of sensing devices that would incorporate CPEs and would be potentially useful for the specific detection of a wide range of bioanalytes. This journal is

Synthesis of sorafenib analogues incorporating a 1,2,3-triazole ring and cytotoxicity towards hepatocellular carcinoma cell lines

A series of 1,2,3-triazole-containing Sorafenib analogues, in which the aryl urea moiety of Sorafenib (1) was replaced with a 1,2,3-triazole ring linking a substituted phenoxy fragment, were prepared successfully via Huisgen 1,3-dipolar cycloaddition and

Enantioselective Palladium-Catalyzed Hydrophosphinylation of Allenes with Phosphine Oxides: Access to Chiral Allylic Phosphine Oxides

A Pd-catalyzed hydrophosphinylation of alkyl and aryl-oxyallenes with phosphine oxides has been developed for the efficient and rapid construction of a family of chiral allylic phosphine oxides with a diverse range of functional groups. This methodology was further applied in the facile construction of chiral 2H-chromene and later stage functionalization of cholesterol.