33171-13-0Relevant articles and documents
Rational Design of Cholesterol Derivative for Improved Stability of Paclitaxel Cationic Liposomes
Monpara, Jasmin,Kanthou, Chryso,Tozer, Gillian M.,Vavia, Pradeep R.
, (2018)
Purpose: This work explores synthesis of novel cholesterol derivative for the preparation of cationic liposomes and its interaction with Paclitaxel (PTX) within liposome membrane using molecular dynamic (MD) simulation and in-vitro studies. Methods: Chole
Method for producing ester based on eco-friendly and high efficiency esterification by using base exchange of salt and the compound thereof
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Paragraph 0109-0115; 0117, (2021/07/07)
The present invention relates to an esterification reaction-based eco-friendly and high efficiency ester compound using ion exchange and an ester compound thereof. The esterification generally proceeds by reverse reaction with water, resulting in poor yield of the ester. In order to avoid hydrolysis, the esterification reaction was environmentally or non-limited due to the continuous supply of hydrochloric acid gas or the use of chlorinated thionyl chloride as a noxious substance. To the present invention, a continuous hydrochloric acid gas is provided by ion exchange of a salt, and magnesium sulfate acts as a dehydrating agent to remove water generated in esterification. In addition, the reactants are cheap and the product is also low in harmfulness and easier to handle and thus more efficient reaction is possible.
-alkyl acyl arginine ester antibacterial agent, and preparation and application thereofN
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Paragraph 0048; 0049, (2019/01/04)
The invention belongs to the field of bactericides, and specifically discloses an N-alkyl acyl arginine ester antibacterial agent. The acyl group part of the N-alkyl acyl arginine esterantibacterial agent is an alkyl group with a carbon atom number of no less than 14; and the ester group part of the N-alkyl acyl arginine ester antibacterial agent is an alkyl group with a carbon atom number of no less than 2. In addition, the invention also provides a preparation method for the antibacterial agent and an application of the antibacterial agent used as a bactericide. The antibacterial agent provided by the invention is creatively discovered that the long-carbon-chain acryl group with the above-mentioned carbon atom number and the ester group with the above-mentioned carbon atom number have excellent synergistic effect and can unexpectedly and significantly shorten antibacterial time under the premise of improving antibacterial performance.