331991-61-8

Basic information

• Product Name: ethyl 3-phenyl-4-(3,5-dimethylpyrazol-1-yl)-4-oxobutanoate
• Synonyms: ethyl 3-phenyl-4-(3,5-dimethylpyrazol-1-yl)-4-oxobutanoate
• CAS NO: 331991-61-8
• Molecular Weight: 300.357
• Mol File: 331991-61-8.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: ethyl 3-phenyl-4-(3,5-dimethylpyrazol-1-yl)-4-oxobutanoate(CAS DataBase Reference)
• NIST Chemistry Reference: ethyl 3-phenyl-4-(3,5-dimethylpyrazol-1-yl)-4-oxobutanoate(331991-61-8)
• EPA Substance Registry System: ethyl 3-phenyl-4-(3,5-dimethylpyrazol-1-yl)-4-oxobutanoate(331991-61-8)

Safety Data

• Hazardous Substances Data: 331991-61-8(Hazardous Substances Data)

Upstream product

• 103-80-0 phenylacetyl chloride 
• 36140-84-8 1-(3,5-dimethyl-1H-pyrazol-1-yl)-2-phenylethan-1-one 
• 105-36-2 ethyl bromoacetate 
• 67-51-6 3,5-dimethyl-1H-pyrazole 

Downstream Products

• 53647-50-0 ethyl 3-benzoyl-3-phenylpropionate 
• 63795-90-4 3-phenyl-4-oxopentanoic acid ethyl ester 

Relevant articles and documents

Preparation of β-substituted γ-keto esters by the grignard reaction on N-acylpyrazoles

Various γ-keto esters were prepared by either the alcoholysis of N-(4-oxoalkanoyl)pyrazoles or the Grignard replacement of pyrazole moiety of 4-(N-pyrazolyl)-4-oxoalkanoic esters. By using 3-phenyl-ι-menthopyrazole as a chiral auxiliary, β-substituted γ-keto esters were enantioselectively obtained.