333754-43-1

Basic information

• Product Name: (1S,2S,3R,4S,5R,8R,9S,10R,13S)-4-acetoxy-2-benzoyloxy-9,10-[(1S)-2-(dimethylamino)ethylidenedioxy]-5,20-epoxy-1-hydroxytax-11-en-13-yl (2R,3S)-3-(tert-butoxycarbonylamino)-3-(3-fluoro-2-pyridyl)-2-triisopropylsilyloxypropionate
• Synonyms: (1S,2S,3R,4S,5R,8R,9S,10R,13S)-4-acetoxy-2-benzoyloxy-9,10-[(1S)-2-(dimethylamino)ethylidenedioxy]-5,20-epoxy-1-hydroxytax-11-en-13-yl (2R,3S)-3-(tert-butoxycarbonylamino)-3-(3-fluoro-2-pyridyl)-2-triisopropylsilyloxypropionate
• CAS NO: 333754-43-1
• Molecular Weight: 1038.34
• Mol File: 333754-43-1.mol
• Article Data: 2

Chemical Properties

• CAS DataBase Reference: (1S,2S,3R,4S,5R,8R,9S,10R,13S)-4-acetoxy-2-benzoyloxy-9,10-[(1S)-2-(dimethylamino)ethylidenedioxy]-5,20-epoxy-1-hydroxytax-11-en-13-yl (2R,3S)-3-(tert-butoxycarbonylamino)-3-(3-fluoro-2-pyridyl)-2-triisopropylsilyloxypropionate(CAS DataBase Reference)
• NIST Chemistry Reference: (1S,2S,3R,4S,5R,8R,9S,10R,13S)-4-acetoxy-2-benzoyloxy-9,10-[(1S)-2-(dimethylamino)ethylidenedioxy]-5,20-epoxy-1-hydroxytax-11-en-13-yl (2R,3S)-3-(tert-butoxycarbonylamino)-3-(3-fluoro-2-pyridyl)-2-triisopropylsilyloxypropionate(333754-43-1)
• EPA Substance Registry System: (1S,2S,3R,4S,5R,8R,9S,10R,13S)-4-acetoxy-2-benzoyloxy-9,10-[(1S)-2-(dimethylamino)ethylidenedioxy]-5,20-epoxy-1-hydroxytax-11-en-13-yl (2R,3S)-3-(tert-butoxycarbonylamino)-3-(3-fluoro-2-pyridyl)-2-triisopropylsilyloxypropionate(333754-43-1)

Safety Data

• Hazardous Substances Data: 333754-43-1(Hazardous Substances Data)

Upstream product

• 1353548-62-5 C₂₉H₃₆O₉ 
• 1353548-63-6 C₃₃H₄₃NO₉ 
• 184586-82-1 C₃₂H₄₀O₉ 
• 173422-30-5 (1S,2S,3R,4S,5R,7S,8R,10R,13S)-4-acetoxy-2-benzoyloxy-5,20-epoxy-9-oxo-1,10,13-trihydroxytax-11-ene 
• 272129-02-9 (1S,2S,3R,4S,5R,7S,8R,10R,13S)-4-acetoxy-2-benzoyloxy-5,20-epoxy-9-oxo-1,10,13-trihydroxytax-6,11-diene 
• 170575-25-4 7-OTf-10DAB 
• 184586-81-0 (1S,2S,3R,4S,5R,8R,9S,10R,13S)-4-(acetoxy)-2-(benzoyloxy)-5,20-epoxy-1,9,10,13-tetrahydroxytax-11-ene 
• 868847-44-3 S-(4-bromophenyl) (2R,3S)-3-[(tert-butoxycarbonyl)amino]-3-(3-fluoro-2-pyridinyl)-2-[(triisopropylsilyl)oxy]propanethioate 
• 1353548-60-3 C₃₃H₄₅NO₉ 
• 457962-01-5 (3R,4S)-cis-4-(3-fluoro-pyridin-2-yl)-3-triisopropylsilyloxy-2-azetidinone 
• 333754-33-9 (3R,4S)-cis-1-(t-butoxycarbonyl)-4-(3-fluoro-pyridin-2-yl)-3-triisopropylsilyloxy-2-azetidinone 
• 162475-68-5 10-deacetyl-9β-dihydrobaccatin III 
• 24424-99-5 di-tert-butyl dicarbonate 
• 32981-86-5 10-deacetylbaccatin III 

Relevant articles and documents

Taxane Compounds, Compositions And Methods

The present invention provides a method for the preparation of orally available pentacyclic taxane compounds, as well as intermediates useful in their preparation.