33390-80-6

Basic information

• Product Name: 2-(2-METHOXYPHENYL)-ACETAMIDE
• Synonyms: 2-(2-METHOXYPHENYL)-ACETAMIDE;2-Methoxybenzeneacetamide
• CAS NO: 33390-80-6
• Molecular Formula: C₉H₁₁NO₂
• Molecular Weight: 165.19
• EINECS: 251-491-5
• Mol File: 33390-80-6.mol
• Article Data: 6

Chemical Properties

• Boiling Point: 339 °C at 760 mmHg
• Flash Point: 187.3 °C
• Appearance: /
• Density: 1.123 g/cm³
• Vapor Pressure: 9.49E-05mmHg at 25°C
• Refractive Index: 1.538
• CAS DataBase Reference: 2-(2-METHOXYPHENYL)-ACETAMIDE(CAS DataBase Reference)
• NIST Chemistry Reference: 2-(2-METHOXYPHENYL)-ACETAMIDE(33390-80-6)
• EPA Substance Registry System: 2-(2-METHOXYPHENYL)-ACETAMIDE(33390-80-6)

Safety Data

• Hazardous Substances Data: 33390-80-6(Hazardous Substances Data)

Usage

General Description

2-(2-Methoxyphenyl)acetamide is a chemical compound with the molecular formula C10H13NO2. It is a white to light yellow crystalline powder that is used in the pharmaceutical industry as an intermediate for the synthesis of various pharmaceuticals and agrochemicals. 2-(2-METHOXYPHENYL)-ACETAMIDE is also known as O-Acetylanisole and is used as a flavoring agent in the food industry. It has analgesic and anti-inflammatory properties and has been studied for potential applications in the treatment of pain and inflammation. Additionally, 2-(2-Methoxyphenyl)acetamide has been investigated for its potential use as a precursor in the synthesis of novel compounds with biological activity.

InChI:InChI=1/C9H11NO2/c1-12-8-5-3-2-4-7(8)6-9(10)11/h2-5H,6H2,1H3,(H2,10,11)

Upstream product

• 7035-03-2 2-methoxy-benzeneacetonitrile 
• 93-25-4 2-methoxyphenylacetic acid 
• 28033-63-8 2-(2-methoxyphenyl)acetyl chloride 
• 7169-17-7 2-diazo-1-(2-methoxyphenyl)ethanone 
• 27798-60-3 methyl 2-(2-methoxyphenyl)acetate 

Downstream Products

• 914645-37-7 4-Methoxy-phthalid 
• 135911-02-3 (3AR,7AR)-7,7,diphenyl-2-[1-imino-2-(2-methoxyphenyl)ethyl]perhydroisoindol-4-one 
• 62115-71-3 2-(2-methoxyphenyl)propanenitrile 
• 7035-03-2 2-methoxy-benzeneacetonitrile 
• 1443982-59-9 C₄₉H₄₈N₂O₁₀ 
• 1443982-57-7 C₁₉H₁₄N₂O₃ 
• 1443982-61-3 C₂₅H₂₄N₂O₇ 
• 634604-89-0 3-(2-methoxyphenyl)-4-[1-(5-pyrimidinyl)-1H-indol-3-yl]-1H-pyrrole-2,5-dione 
• 634604-98-1 5-{5-chloro-3-[4-(2-methoxyphenyl)-2,5-dioxo-2,5-dihydro-1H-pyrrol-3-yl]-indol-1-yl}-nicotinic acid methyl ester 
• 22446-40-8 2-(2-hydroxyphenyl)acetamide 

Relevant articles and documents

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Sodium azide as a catalyst for the hydration of nitriles to primary amides in water

The selective conversion of aromatic nitriles to primary amides has been accomplished using sodium azide. The corresponding amides were obtained efficiently in excellent yields. This reaction was carried out under eco-friendly conditions using water in the absence of organic solvents.

Novel 3-azaindolyl-4-arylmaleimides exhibiting potent antiangiogenic efficacy, protein kinase inhibition, and antiproliferative activity

Tumor growth and metastasis are highly associated with the overexpression of protein kinases (PKs) regulating cell growth, apoptosis resistance, and prolonged cell survival. This study describes novel azaindolyl-maleimides with significant inhibition of PKs, such as VEGFR, FLT-3, and GSK-3β which are related to carcinogenesis. Furthermore, these compounds exhibit high kinase selectivity and potent inhibition of angiogenesis and cell proliferation, offering versatile options in cancer treatment strategies.