335059-94-4

Basic information

• Product Name: CarbaMic acid, N-[2-[[(4-chlorophenyl)Methyl]aMino]ethyl]-, 1,1-diMethylethyl ester
• Synonyms: CarbaMic acid, N-[2-[[(4-chlorophenyl)Methyl]aMino]ethyl]-, 1,1-diMethylethyl ester;tert-Butyl (2-((4-chlorobenzyl)aMino)ethyl)carbaMate;tert-Butyl N-[2-[(4-chlorophenyl)methylamino]ethyl]carbamate
• CAS NO: 335059-94-4
• Molecular Formula: C₁₄H₂₁ClN₂O₂
• Molecular Weight: 284.78174
• Mol File: 335059-94-4.mol
• Article Data: 6

Chemical Properties

• Appearance: /
• CAS DataBase Reference: CarbaMic acid, N-[2-[[(4-chlorophenyl)Methyl]aMino]ethyl]-, 1,1-diMethylethyl ester(CAS DataBase Reference)
• NIST Chemistry Reference: CarbaMic acid, N-[2-[[(4-chlorophenyl)Methyl]aMino]ethyl]-, 1,1-diMethylethyl ester(335059-94-4)
• EPA Substance Registry System: CarbaMic acid, N-[2-[[(4-chlorophenyl)Methyl]aMino]ethyl]-, 1,1-diMethylethyl ester(335059-94-4)

Safety Data

• Hazardous Substances Data: 335059-94-4(Hazardous Substances Data)

Usage

General Description

CarbaMic acid, N-[2-[[(4-chlorophenyl)Methyl]aMino]ethyl]-, 1,1-diMethylethyl ester is a chemical compound that belongs to the class of carboxylic acid esters. It is derived from CarbaMic acid and 1,1-diMethylethyl alcohol. This chemical is commonly used as a pharmaceutical intermediate and can be found in various drug formulations. It may also have potential applications in research and development for pharmaceutical products. Additionally, it is important to handle and use this chemical with care and in accordance with safety procedures to minimize any potential health and environmental risks.

Upstream product

• 215654-54-9 C₁₄H₁₉ClN₂O₂ 
• 57260-73-8 N-BOC-1,2-diaminoethane 
• 104-88-1 4-chlorobenzaldehyde 
• 104-83-6 1-Chloro-4-(chloromethyl)benzene 

Downstream Products

• 1097834-07-5 benzyl 4-((2-(tert-butoxycarbonylamino)ethyl)(4-chlorobenzyl)carbamoyl)piperazine-1-carboxylate 
• 60927-95-9 1-(4-chlorobenzyl)imidazolidin-2-one 
• 853686-95-0 N-(2-amino-ethyl)-N-(4-chlorobenzyl)-4-pyridin-4-yl-benzamide 
• 853680-69-0 {2-[(4-chlorobenzyl)-(4-pyridin-4-yl-benzoyl)-amino]-ethyl}-carbamic acid tert-butyl ester 
• 335059-97-7 {2-[(2-amino-4-methyl-pentanoyl)-(4-chloro-benzyl)-amino]-ethyl}-carbamic acid tert-butyl ester 

Relevant articles and documents

Inhibitory effect of novel tetrahydropyrimidine-2(1H)-thiones on melanogenesis

The series of imidazoldine-2-thiones 2 and tetrahydropyrimidine-2-thiones 3 were discovered as inhibitor of α-MSH-induced melanin production in melanoma B16 cells. The primary bioassay showed that 1-(4-ethylbenzyl)-tetrahydropyrimidine-2(1H)-thione 3e (>1

SUBSTITUTED 4-BENZYLOXY-BENZOIC ACID AMIDE DERIVATIVES

The present invention relates to novel substituted 4-benzyloxy-benzoic acid amide derivatives, processes for their preparation, and their use in medicaments, especially for the prophylaxis and treatment of diseases associated with Cold Menthol Receptor 1 (CMR-1) activity, in particular for the treatment of urological diseases or disorders, such as detrusor overactivity (overactive bladder), urinary incontinence, neurogenic detrusor overactivity (detrusor hyperflexia), idiopathic detrusor overactivity (detrusor instability), benign prostatic hyperplasia, and lower urinary tract symptoms; chronic pain, neuropathic pain, postoperative pain, rheumatoid arthritic pain, neuralgia, neuropathies, algesia, nerve injury, ischaemia, neurodegeneration, stroke, and inflammatory disorders such as asthma and chronic obstructive pulmonary (or airways) disease (COPD).

AKT PROTEIN KINASE INHIBITORS

The present invention provides compounds, including resolved enantiomers, diastereomers, solvates and pharmaceutically acceptable salts thereof, comprising the Formula: A-L-CR where CR is a cyclical core group, L is a linking group and A is as defined herein. Also provided are methods of using the compounds of this invention as AKT protein kinase inhibitors and for the treatment of hyperproliferative diseases such as cancer.