33608-93-4

Basic information

• Product Name: 1H-Isoindol-1-one, 2,3-dihydro-3-(phenylmethylene)-, (E)-
• CAS NO: 33608-93-4
• Molecular Formula: C15H11NO
• Molecular Weight: 221.258
• Mol File: 33608-93-4.mol
• Article Data: 10

Chemical Properties

• CAS DataBase Reference: 1H-Isoindol-1-one, 2,3-dihydro-3-(phenylmethylene)-, (E)-(CAS DataBase Reference)
• NIST Chemistry Reference: 1H-Isoindol-1-one, 2,3-dihydro-3-(phenylmethylene)-, (E)-(33608-93-4)
• EPA Substance Registry System: 1H-Isoindol-1-one, 2,3-dihydro-3-(phenylmethylene)-, (E)-(33608-93-4)

Safety Data

• Hazardous Substances Data: 33608-93-4(Hazardous Substances Data)

Upstream product

• 136918-14-4 phthalimide 
• 100-52-7 benzaldehyde 
• 60901-21-5 o-styrylbenzoic acid 
• 1084-95-3 2-(2'-phenylethynyl)benzoic acid 
• 33578-05-1 methyl 2-(phenylethynyl)benzoate 
• 14178-42-8 2-benzamidopyridine 1-oxide 
• 65-85-0 benzoic acid 
• 1225463-02-4 2-iodo-N-methoxybenzamide 
• 536-74-3 phenylacetylene 
• 20871-31-2 2,3-dihydro-3-hydroxy-3-(phenylmethyl)-1H-isoindol-1-one 
• 5159-41-1 2-iodobenzyl alcohol 
• 891194-31-3 C₁₁H₁₂INO₄ 
• 891194-28-8 methyl 1-oxo-1,3-dihydro-2H-isoindole-2-carboxylate 
• 103-82-2 phenylacetic acid 

Downstream Products

• 40523-32-8 3-(phenylmethylene)isoindol-1-one 

Relevant articles and documents

Stepwise synthesis and spectral characteristics of meso-trans-diphenyldi(1- naphthyl)tetrabenzoporphin and its zinc complex

A reaction of phthalimide with phenylacetic acid in the presence of zinc oxide furnished 3-oxoisoindolenyl-3′-oxoisoindolinylidene-1,1′- benzylidine which at heating with 1-naphthylacetic acid in the presence of zinc oxide provided zinc meso-trans-diphenyldi(1-naphthyl)tetrabenzoporphin complex. Proceeding from this compound a meso-trans-diphenyldi(1-naphthyl) tetrabenzoporphin was prepared. The spectral characteristics of compounds obtained were studied.

Synthesis of Secondary Unsaturated Lactams via an Aza-Heck Reaction

The preparation of unsaturated secondary lactams via the palladium-catalyzed cyclization of O-phenyl hydroxamates onto a pendent alkene is reported. This method provides rapid access to a broad range of lactams that are widely useful building blocks in alkaloid synthesis. Mechanistic studies support an aza-Heck-type pathway.

Reductive coupling of phthalimides with ketones and aldehydes by low-valent titanium: One-pot synthesis of alkylideneisoindolin-1-ones

The reductive coupling of phthalimides with ketones and aldehydes by Zn-TiCl4 in THF gave two- and four-electron reduced products, 3-hydroxy-3-(1-hydroxyalkyl)isoindolin-1-ones and alkylideneisoindolin-1-ones, selectively by controlling the rea