33737-08-5

Basic information

• Product Name: 1,2-O-isopropylidene-6-O-trityl-α-D-glucofuranoside
• Synonyms: 1,2-O-isopropylidene-6-O-trityl-α-D-glucofuranoside
• CAS NO: 33737-08-5
• Molecular Weight: 462.543
• Mol File: 33737-08-5.mol
• Article Data: 8

Chemical Properties

• CAS DataBase Reference: 1,2-O-isopropylidene-6-O-trityl-α-D-glucofuranoside(CAS DataBase Reference)
• NIST Chemistry Reference: 1,2-O-isopropylidene-6-O-trityl-α-D-glucofuranoside(33737-08-5)
• EPA Substance Registry System: 1,2-O-isopropylidene-6-O-trityl-α-D-glucofuranoside(33737-08-5)

Safety Data

• Hazardous Substances Data: 33737-08-5(Hazardous Substances Data)

Upstream product

• 76-83-5 trityl chloride 
• 18549-40-1 1,2-O-isopropylidene-α-D-glucofuranose 
• 582-52-5 1,2:5,6-di-O-isopropylidene-α-D-glucofuranose 
• 252057-03-7 1,2-O-isopropylidene-5,6-di-O-trityl-α-D-glucofuranose 
• 252057-02-6 1,2-O-isopropylidene-3,6-di-O-trityl-α-D-glucofuranose 
• 29364-56-5 3,5,6-tri-O-acetyl-1,2-O-isopropylidene-α-D-glucofuranose 

Downstream Products

• 120679-80-3 methyl 3,5-di-O-benzyl-β-D-glucofuranoside 
• 120679-79-0 methyl 3,5-di-O-benzyl-α-D-glucofuranoside 
• 35927-26-5 methyl 3,5-di-O-benzyl-2,6-di-O-methyl-α-D-glucofuranoside 
• 68095-73-8 3,5-Di-O-acetyl-1,2-O-isopropyliden-6-O-trityl-α-D-glucofuranose 
• 28713-38-4 3,5-di-O-benzyl-1,2-O-isopropylidene-6-O-trityl-α-D-glucofuranose 
• 50908-07-1 3,5-O-benzylidene-1,2-O-isopropylidene-6-O-trityl-α-D-glucofuranose 
• 67692-96-0 O¹,O²-isopropylidene-O³,O⁵-dimethyl-O⁶-trityl-α-D-glucofuranose 
• 18549-40-1 1,2-O-isopropylidene-α-D-glucofuranose 

Relevant articles and documents

Isonucleosides: Design and synthesis of new isomeric nucleosides with antiviral potential

Isonucleosides discovered in our laboratory have been found to have interesting antiviral activity. The design, development of methodology, and stereochemical synthesis of new isonucleosides of anti-HCV interest are described. Antiviral results are cited.

Novel selectivity in carbohydrate reactions, IV: DABCO-mediated regioselective primary hydroxyl protection of carbohydrates

An efficient procedure for the regioselective tritylation of primary hydroxyl group of aldohexopyranosides and nucleosides using trityl chloride in the presence of 1,4-diazabicyclo[2.2.2]octane (DABCO) in dichloromethane has been developed. Subsequent acetylation of the tritylated products in the same pot has been made possible, thereby providing an efficient route to the fully protected carbohydrate derivatives that can be discriminated chemoselectively.

Stereospecific synthesis of (+)-muscarine from D-glucose, suitable for preparation of 5-substituted analogues

A stereospecific synthesis of (+)-muscarine iodide (1) has been achieved starting from D-glucose as a chiral precursor. The key steps of the synthesis involved a stereospecific cyclization of 3,5-di-O-mesyl derivative 3 into the 2,5-anhydride 4, the stereospecific catalytic hydrogenation of unsaturated derivative 6, and the C-4 epimerization of alcohol 12 by Mitsunobu reaction.