339-16-2 Usage
Description
Retinoic acid, methyl ester, also known as all-trans-Retinoic Acid Methyl Ester (CAS# 339-16-2), is a chemical compound that is classified as a yellow solid. It is primarily used in organic synthesis and has various applications across different industries due to its unique chemical properties.
Uses
Used in Organic Synthesis:
Retinoic acid, methyl ester is used as a synthetic intermediate for the production of various compounds in the field of organic synthesis. Its chemical structure allows it to be a versatile building block in the creation of a wide range of molecules, including pharmaceuticals, agrochemicals, and other specialty chemicals.
Used in Pharmaceutical Industry:
Retinoic acid, methyl ester is used as an active pharmaceutical ingredient (API) for the development of drugs that target various health conditions. Its role in the synthesis of these drugs is crucial, as it can be modified and combined with other molecules to create effective treatments.
Used in Cosmetics Industry:
In the cosmetics industry, Retinoic acid, methyl ester is used as a key ingredient in anti-aging and skin care products. Its ability to promote cell turnover and improve skin texture makes it a valuable component in formulations designed to reduce the appearance of fine lines, wrinkles, and other signs of aging.
Used in Research and Development:
Retinoic acid, methyl ester is also utilized in research and development settings, where it serves as a valuable tool for studying the effects of retinoids on cellular processes and understanding their potential applications in medicine and other fields.
Check Digit Verification of cas no
The CAS Registry Mumber 339-16-2 includes 6 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 3 digits, 3,3 and 9 respectively; the second part has 2 digits, 1 and 6 respectively.
Calculate Digit Verification of CAS Registry Number 339-16:
(5*3)+(4*3)+(3*9)+(2*1)+(1*6)=62
62 % 10 = 2
So 339-16-2 is a valid CAS Registry Number.
InChI:InChI=1/C21H30O2/c1-16(9-7-10-17(2)15-20(22)23-6)12-13-19-18(3)11-8-14-21(19,4)5/h7,9-10,12-13,15H,8,11,14H2,1-6H3/b10-7+,13-12+,16-9+,17-15+
339-16-2Relevant articles and documents
Visual Pigments. 11. Spectroscopy and Photophysics of Retinoic Acids and all-trans-Methyl Retinoate
Takemura, T.,Chihara, K.,Becker, Ralph S.,Das, P.K.,Hug, G.L.
, p. 2604 - 2609 (1980)
The photophysics of hydrogen-bonded complexes of retinoic acid and its 9-cis and 13-cis isomers and the photophysics of the dimers of these isomers of retinoic acid were studied.The ivestigation indicated that complexes of retinoic acid and molecules that
Imidazotetrazines as Weighable Diazomethane Surrogates for Esterifications and Cyclopropanations
Svec, Riley L.,Hergenrother, Paul J.
supporting information, p. 1857 - 1862 (2019/12/27)
Diazomethane is one of the most versatile reagents in organic synthesis, but its utility is limited by its hazardous nature. Although alternative methods exist to perform the unique chemistry of diazomethane, these suffer from diminished reactivity and/or correspondingly harsher conditions. Herein, we describe the repurposing of imidazotetrazines (such as temozolomide, TMZ, the standard of care for glioblastoma) for use as synthetic precursors of alkyl diazonium reagents. TMZ was employed to conduct esterifications and metal-catalyzed cyclopropanations, and results show that methyl ester formation from a wide variety of substrates is especially efficient and operationally simple. TMZ is a commercially available solid that is non-explosive and non-toxic, and should find broad utility as a replacement for diazomethane.
Correlation of fluorescence quenching in carotenoporphyrin dyads with the energy of intramolecular charge transfer states. Effect of the number of conjugated double bonds of the carotenoid moiety
Fungo, Fernando,Otero, Luis,Durantini, Edgardo,Thompson, William J.,Silber, Juana J.,Moore, Thomas A.,Moore, Ana L.,Gust, Devens,Sereno, Leonides
, p. 469 - 475 (2007/10/03)
The electrochemistry of a series of non-symmetric synthetic carotenoids, with different conjugated double bounds chain lengths (5 to 11) is reported. The values of the first oxidation potentials of the carotenoids were evaluated by digital simulation of t