34047-62-6

Basic information

• Product Name: L-erythro-3-(3,4-Dihydroxyphenyl)serine
• Synonyms: erythro-Dopaserine;L-erythro-3-(3,4-Dihydroxyphenyl)serine;L-erythro-3,4-Dihydroxyphenylserine;L-Tyrosine, β,3-dihydroxy-, erythro-;Serine, 3-(3,4-dihydroxyphenyl)-, L-erythro- (8CI)
• CAS NO: 34047-62-6
• Molecular Formula: C₉H₁₁NO₅
• Molecular Weight: 213.19
• Mol File: 34047-62-6.mol
• Article Data: 5

Chemical Properties

• Boiling Point: 549.8±50.0 °C(Predicted)
• Appearance: /
• Density: 1.608±0.06 g/cm3(Predicted)
• PKA: 2.09±0.24(Predicted)
• CAS DataBase Reference: L-erythro-3-(3,4-Dihydroxyphenyl)serine(CAS DataBase Reference)
• NIST Chemistry Reference: L-erythro-3-(3,4-Dihydroxyphenyl)serine(34047-62-6)
• EPA Substance Registry System: L-erythro-3-(3,4-Dihydroxyphenyl)serine(34047-62-6)

Safety Data

• Hazardous Substances Data: 34047-62-6(Hazardous Substances Data)

Usage

Description

L-erythro-3-(3,4-Dihydroxyphenyl)serine, also known as erythro-β,3-Dihydroxy-L-tyrosine, is an organic compound with a unique structure that features a serine molecule with a 3,4-dihydroxyphenyl group attached to it. L-erythro-3-(3,4-Dihydroxyphenyl)serine has been found to have significant biological activities and potential applications in various fields.

Uses

Used in Pharmaceutical Applications:
L-erythro-3-(3,4-Dihydroxyphenyl)serine is used as a therapeutic agent for the treatment of neurological disorders. It has been shown to inhibit methamphetamine-induced locomotor activity and decrease brain dopamine content when administered to rats, suggesting its potential in managing conditions related to dopamine dysregulation.
Used in Research and Development:
L-erythro-3-(3,4-Dihydroxyphenyl)serine is also utilized in research settings to study the effects of various substances on dopamine levels and neurotransmission. Its ability to modulate dopamine content in the brain makes it a valuable tool for understanding the underlying mechanisms of neurochemical interactions and the development of novel treatments for related disorders.

Upstream product

• 173597-41-6 3,4-Dicarboethoxymethylenedioxybenzaldehyde 
• 50-81-7 ascorbic acid 
• 139-85-5 3,4-dihydroxybenzaldehyde 
• 5447-02-9 3,4-dibenzyloxybenzaldehyde 
• 55449-18-8 (2RS.3RS)-2-amino-3-(3,4-bis-benzyloxy-phenyl)-3-hydroxy-propionic acid 
• 113139-62-1 3,4-bis(ethoxycarboxy)-benzaldehyde 
• 55449-18-8 D,L-threo-3-(3,4-Dibenzyloxyphenyl)serine 

Relevant articles and documents

Synthesis of 2- and 6-fluoro analogues of threo-3-(3,4-dihydroxyphenyl)serine (2- and 6-fluoro-threo-DOPS)

2-Fluoro- and 6-fluoro-threo-dihydroxyphenylserine (2-F- and 6-F-threo-DOPS) have the potential, after crossing the blood-brain barrier, of functioning in the central nervous system as biological precursors of 2- and 6-fluoronorepinephrine (2- and 6-F-NE)

Process for producing 3-(3,4-dihydroxyphenyl) serine

A process for producing racemic or optically active threo- or erythro-3-(3,4-dihydroxyphenyl)serine which comprises phthaloylating the amine group of a racemic or optically active threo- or erythro-3-(3,4-dihydroxyphenyl)serine derivative to yield a racem

Process for the production of optically active threo-3-(3,4-dihydroxyphenyl)serine

Improved process for the production of optical aCTIVE (D- or L-) threo-3-(3,4-dihydroxyphenyl)serine, which comprises subjecting racemic threo-3-(3,4-dibenzyloxyphenyl)-N-carbobenzyloxyserine to optical resolution by using as a resolving reagent an optical active amino alcohol derivative, and then subjecting the resulting optical active (D- or L-) threo-3-(3,4-dibenzyloxyphenyl)-N-carbobenzyloxyserine to hydrogenolysis.