3405-45-6Relevant articles and documents
Illuminati,Lillocci
, p. 2201 (1977)
Mild Hydrogenation of Amides to Amines over a Platinum-Vanadium Bimetallic Catalyst
Mitsudome, Takato,Miyagawa, Kazuya,Maeno, Zen,Mizugaki, Tomoo,Jitsukawa, Koichiro,Yamasaki, Jun,Kitagawa, Yasutaka,Kaneda, Kiyotomi
supporting information, p. 9381 - 9385 (2017/08/01)
Hydrogenation of amides to amines is an important reaction, but the need for high temperatures and H2 pressures is a problem. Catalysts that are effective under mild reaction conditions, that is, lower than 30 bar H2 and 70 °C, have not yet been reported. Here, the mild hydrogenation of amides was achieved for the first time by using a Pt-V bimetallic catalyst. Amide hydrogenation, at either 1 bar H2 at 70 °C or 5 bar H2 at room temperature was achieved using the bimetallic catalyst. The mild reaction conditions enable highly selective hydrogenation of various amides to the corresponding amines, while inhibiting arene hydrogenation. Catalyst characterization showed that the origin of the catalytic activity for the bimetallic catalyst is the oxophilic V-decorated Pt nanoparticles, which are 2 nm in diameter.
N-Methylation of amines with methanol in a hydrogen free system on a combined Al2O3-mordenite catalyst
Su, Jiahui,Li, Xungang,Chen, Yunbin,Cui, Yuancun,Xu, Jingwei,Qian, Chao,Chen, Xinzhi
, p. 55643 - 55649 (2016/07/06)
N-Methyl amines play a major role in the production of medicines, pesticides, surfactants and dyes. N-Methylation of primary or second amines with methanol is considered to be a green path for the synthesis of N-methyl amines and the catalyst is key. In this article, the combined Al2O3-mordenite catalyst (mass fraction of alumina is 40%) with good activity, selectivity, lifetime and stability was prepared for N-methylation of various amines with methanol in a hydrogen free system in a fixed bed reactor, and characterized by XRD, N2 adsorption and NH3-TPD. Furthermore, the methanol adsorption was investigated by in situ FTIR, and the result indicated that methoxyl species may be the active species for the N-methylation of amines.
