34114-57-3

Basic information

• Product Name: N-(1-hydroxybutan-2-yl)-2-phenylacetamide
• Synonyms: N-(1-hydroxybutan-2-yl)-2-phenylacetamide
• CAS NO: 34114-57-3
• Molecular Weight: 207.272
• Mol File: 34114-57-3.mol
• Article Data: 3

Chemical Properties

• CAS DataBase Reference: N-(1-hydroxybutan-2-yl)-2-phenylacetamide(CAS DataBase Reference)
• NIST Chemistry Reference: N-(1-hydroxybutan-2-yl)-2-phenylacetamide(34114-57-3)
• EPA Substance Registry System: N-(1-hydroxybutan-2-yl)-2-phenylacetamide(34114-57-3)

Safety Data

• Hazardous Substances Data: 34114-57-3(Hazardous Substances Data)

Upstream product

• 96-20-8 2-aminobutanol 
• 101-97-3 Ethyl 2-phenylethanoate 
• 101-41-7 benzeneacetic acid methyl ester 
• 103-82-2 phenylacetic acid 

Downstream Products

• 5856-62-2 (S)-2-aminobutan-1-ol 
• 5856-63-3 (2R)-2-aminobutan-1-ol 

Relevant articles and documents

Resolution of racemic 2-amino-1-butanol with immobilised penicillin G acylase

Racemic 2-amino-1-butanol has been resolved to obtain (S)-2-amino-1- butanol with >99% e.e. via enantioselective hydrolysis of its N-phenylacetyl derivative with penicillin G acylase immobilised on Eupergit C. (C) 1999 Elsevier Science Ltd.

Ammonium nitrate: A biodegradable and efficient catalyst for the direct amidation of esters under solvent-free conditions

A simple, metal-free, and environment-friendly procedure is developed for the direct conversion of esters to amides using ammonium nitrate as a catalyst under solvent-free conditions. Aryls, heteroaryls, and aliphatic esters are easily converted to the corresponding amides in excellent isolated yields (85-99%). An enantiopure ester and amine were both shown to react without racemization. The methodology has been successfully applied to preparation of procainamide.