342421-15-2

Basic information

• Product Name: 5-(2-hydroxyethyl)-9-(3,4,5-trimethoxyphenyl)-6,9-dihydro[1,3]dioxolo[4,5-g]furo[3,4-b]quinolin-8(5H)-one
• Synonyms: 5-(2-hydroxyethyl)-9-(3,4,5-trimethoxyphenyl)-6,9-dihydro[1,3]dioxolo[4,5-g]furo[3,4-b]quinolin-8(5H)-one
• CAS NO: 342421-15-2
• Molecular Weight: 441.438
• Mol File: 342421-15-2.mol
• Article Data: 5

Chemical Properties

• CAS DataBase Reference: 5-(2-hydroxyethyl)-9-(3,4,5-trimethoxyphenyl)-6,9-dihydro[1,3]dioxolo[4,5-g]furo[3,4-b]quinolin-8(5H)-one(CAS DataBase Reference)
• NIST Chemistry Reference: 5-(2-hydroxyethyl)-9-(3,4,5-trimethoxyphenyl)-6,9-dihydro[1,3]dioxolo[4,5-g]furo[3,4-b]quinolin-8(5H)-one(342421-15-2)
• EPA Substance Registry System: 5-(2-hydroxyethyl)-9-(3,4,5-trimethoxyphenyl)-6,9-dihydro[1,3]dioxolo[4,5-g]furo[3,4-b]quinolin-8(5H)-one(342421-15-2)

Safety Data

• Hazardous Substances Data: 342421-15-2(Hazardous Substances Data)

Upstream product

• 4971-56-6 tetrahydrofuran-2,4-dione 
• 86-81-7 3,4,5-trimethoxy-benzaldehyde 
• 81329-90-0 4-(2,hydroxyethyl)amino-1,2-methylenedioxybenzene 
• 14268-66-7 benzo[1,3]dioxolo-5-ylamine 

Relevant articles and documents

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Dihydrofuro[3,4-b]quinolin-1-one compounds

The invention relates to compound of formula (I): wherein: represents a single or double bond, R0represents hydrogen or hydroxy or alkoxy, R1and R2, which are identical or different, each represents hydrogen or halogen or alkyl, alkoxy, hydroxy, polyhaloalkyl, nitro or optionally substituted amino or ?wherein m represents an integer such that 1≦m≦4, or form together with the carbon atoms carrying them an aromatic or non-aromatic, mono- or bi-cyclic group having from 5 to 12 ring members and optionally containing 1 or 2 hetero atoms selected from O, S and N, R3represents hydrogen or aryl, heteroaryl, cycloalkyl, optionally substituted alkyl or a group of formula COR7wherein R7represents aryl, optionally substituted alkyl, optionally substituted amino or OR10wherein R10represents aryl or optionally substituted alkyl, X represents oxygen or sulphur or —CH2— or —CH2—CH2—, Ar represents aryl, heteroaryl or arylalkyl, its optical isomers, its hydrates, solvates, and also its addition salts with a pharmaceutically acceptable acid. Medicinal products containing the same are useful in the treatment of cancer.