81329-90-0Relevant articles and documents
Oxalic amide ligands, and uses thereof in copper-catalyzed coupling reaction of aryl halides
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Page/Page column 85-86, (2020/01/09)
The present invention provides oxalic amide ligands and uses thereof in copper-catalyzed coupling reaction of aryl halides. Specifically, the present invention provides a use of a compound represented by formula I, wherein definitions of each group are described in the specification. The compound represented by formula I can be used as a ligand in copper-catalyzed coupling reaction of aryl halides for the formation of C—N, C—O and C—S bonds.
Antineoplastic Agents. 585. Isolation of Bridelia ferruginea Anticancer Podophyllotoxins and Synthesis of 4-Aza-podophyllotoxin Structural Modifications
Pettit, George R.,Searcy, Justin D.,Tan, Rui,Cragg, Gordon M.,Melody, Noeleen,Knight, John C.,Chapuis, Jean-Charles
, p. 507 - 518 (2016/04/19)
Cytotoxic constituents of the terrestrial plant Bridelia ferruginea were isolated using bioactivity-guided fractionation, which revealed the presence of the previously known deoxypodophyllotoxin (1), isopicrodeoxypodophyllotoxin (2), β-peltatin (3), β-pel
Identification of the first inhibitor of the GBP1:PIM1 interaction. Implications for the development of a new class of anticancer agents against paclitaxel resistant cancer cells
Andreoli, Mirko,Persico, Marco,Kumar, Ajay,Orteca, Nausicaa,Kumar, Vineet,Pepe, Antonella,Mahalingam, Sakkarapalayam,Alegria, Antonio E.,Petrella, Lella,Sevciunaite, Laima,Camperchioli, Alessia,Mariani, Marisa,Di Dato, Antonio,Novellino, Ettore,Scambia, Giovanni,Malhotra, Sanjay V.,Ferlini, Cristiano,Fattorusso, Caterina
, p. 7916 - 7932 (2014/12/10)
Class III β-tubulin plays a prominent role in the development of drug resistance to paclitaxel by allowing the incorporation of the GBP1 GTPase into microtubules. Once in the cytoskeleton, GBP1 binds to prosurvival kinases such as PIM1 and initiates a sig