342421-26-5

Basic information

• Product Name: 9-(4-hydroxy-3,5-dimethoxyphenyl)-5-(2-hydroxyethyl)-6,9-dihydro[1,3]dioxolo[4,5-g]furo[3,4-b]quinolin-8(5H)-one
• CAS NO: 342421-26-5
• Molecular Weight: 427.411
• Mol File: 342421-26-5.mol
• Article Data: 2

Chemical Properties

• CAS DataBase Reference: 9-(4-hydroxy-3,5-dimethoxyphenyl)-5-(2-hydroxyethyl)-6,9-dihydro[1,3]dioxolo[4,5-g]furo[3,4-b]quinolin-8(5H)-one(CAS DataBase Reference)
• NIST Chemistry Reference: 9-(4-hydroxy-3,5-dimethoxyphenyl)-5-(2-hydroxyethyl)-6,9-dihydro[1,3]dioxolo[4,5-g]furo[3,4-b]quinolin-8(5H)-one(342421-26-5)
• EPA Substance Registry System: 9-(4-hydroxy-3,5-dimethoxyphenyl)-5-(2-hydroxyethyl)-6,9-dihydro[1,3]dioxolo[4,5-g]furo[3,4-b]quinolin-8(5H)-one(342421-26-5)

Safety Data

• Hazardous Substances Data: 342421-26-5(Hazardous Substances Data)

Upstream product

• 14268-66-7 benzo[1,3]dioxolo-5-ylamine 
• 4971-56-6 tetrahydrofuran-2,4-dione 
• 81329-90-0 4-(2,hydroxyethyl)amino-1,2-methylenedioxybenzene 
• 134-96-3 syringic aldehyde 

Relevant articles and documents

Identification of the first inhibitor of the GBP1:PIM1 interaction. Implications for the development of a new class of anticancer agents against paclitaxel resistant cancer cells

Class III β-tubulin plays a prominent role in the development of drug resistance to paclitaxel by allowing the incorporation of the GBP1 GTPase into microtubules. Once in the cytoskeleton, GBP1 binds to prosurvival kinases such as PIM1 and initiates a sig