34271-65-3Relevant articles and documents
Oxidative cyclization of 3-oxopropanenitriles with α,β-unsaturated amides by manganese(III) acetate. Regio- and stereoselective synthesis of 4-cyano-2,3-dihydrofuran-3-carboxamides
Burgaz, E. Vildan,Yilmaz, Mehmet,Pekel, A. Tarik,?ktemer, Atilla
, p. 7229 - 7239 (2007)
4-Cyano-2,3-dihydrofuran-3-carboxamides were obtained from the oxidative cyclization of 3-oxopropanenitriles with unsaturated amides using manganese(III) acetate. Treatment of 3-oxopropanenitriles with (2E)-3-(5-methyl-2-furyl)acrylamide and (2E)-3-(2-thi
Solid phase synthesis of alkenes using the Horner-Wadsworth-Emmons reaction and monitoring by gel phase 31P NMR
Johnson,Zhang
, p. 9253 - 9256 (2007/10/02)
Phosphonoacetamide esters bound to solid supported peptides or peptide synthesis supports are active as Horner-Wadsworth-Emmons (HWE) reagents with a variety of aldehydes. HWE reagents can be attached to the solid support via the amide or phosphono ester. Mild basic conditions, triethylamine and Li salts, with excess aldehyde give high conversions to alkenes.